Evidence map›Paper›PMID 30373008›Full record

ArticleFood chemistry2019

Profiling the impact of thermal processing on black raspberry phytochemicals using untargeted metabolomics.

Matthew D Teegarden, Steven J Schwartz, Jessica L Cooperstone

Abstract read
In one paragraph

Article in Food chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
  2. Article
  3. Berries vs. Disease: Revenge of the Phytochemicals.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Matthew D TeegardenDepartment of Food Science and Technology, The Ohio State University, 2015 Fyffe Court, Columbus, OH 43210, USA.
Steven J SchwartzDepartment of Food Science and Technology, The Ohio State University, 2015 Fyffe Court, Columbus, OH 43210, USA.
Jessica L CooperstoneDepartment of Food Science and Technology, The Ohio State University, 2015 Fyffe Court, Columbus, OH 43210, USA; Department of Horticulture and Crop Science, The Ohio State University, 2001 Fyffe Court, Columbus, OH 43210, USA. Electronic address: cooperstone.1@osu.edu.
The Ohio State University · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
Validation studies for interactive omics: Black raspberry metabolites and the oral microbiome in smokersU01CA188250 · NCI · OHIO STATE UNIVERSITY · PI CLINTON, STEVEN K, KUMAR, PURNIMA · 2014 to 2019
$3.6M
NCI NIH HHS P30 CA016058NCI NIH HHS U01 CA188250
6 · The paper itself

Abstract

Clinical and laboratory studies have implicated black raspberries (BRBs) and their associated phytochemicals in the modulation of several chronic diseases. Most research on the health benefits of BRBs is conducted using freeze-dried or otherwise minimally processed products, yet BRBs are typically consumed as thermally processed goods like jams and syrups. The objective of this work was to profile the chemical changes that result from thermal processing of BRB powder into a nectar beverage. Using an untargeted UHPLC-QTOF-MS metabolomics approach, key degradation products of anthocyanins were identified along with several other proposed phenolic degradants. The effects of processing on other key BRB compound groups, including ellagitannins, are also discussed. This work demonstrates the utility of an untargeted metabolomics approach in describing the chemistry of complex food systems and provides a foundation for future research on the impact of processing on BRB product bioactivity.

Indexed as

MetabolomicsTemperatureFood HandlingFruitPhytochemicalsRubusPhytochemicalsAnthocyaninsBlack raspberriesChemical FingerprintingEllagitanninsFlavonoidsMetabolomicsPhytochemicalsRubus occidentalisThermal processing

Identifiers

PMID30373008
PMCPMC6219623
OpenAlexW2890686255

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.