ArticleInvestigative ophthalmology & visual science2018
Ocular Biometric Diurnal Rhythms in Emmetropic and Myopic Adults.
Article in Investigative ophthalmology & visual science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of atropine on changes in choroidal thickness in children with myopia: a meta-analysis of randomized controlled trials.Frontiers in medicine · 2025Pooled it
- Potential Choroidal Mechanisms Underlying Atropine's Antimyopic and Rebound Effects: A Mediation Analysis in a Randomized Clinical Trial.Investigative ophthalmology & visual science · 2023Trial
- Changes in Ocular Biometric Parameters Over a 24-Hour Period in Ocular Hypertensive Patients.Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics · 2022Trial
- Effects of Atropine Treatment on Choroidal Thickness in Myopic Children.Investigative ophthalmology & visual science · 2020Trial
- Longitudinal Changes in Choroidal Thickness Across the Eye in Young Children With Premyopia.Investigative ophthalmology & visual science · 2026Article
- Diurnal Variations in Anterior and Posterior Corneal Thickness and Curvature in Healthy Eyes: Global and Sector-Based Metrics and Lifestyle Associations.Life (Basel, Switzerland) · 2026Article
- Review
- Long-Term Monochromatic Light Exposure Does Not Alter Modular Chromatic Representation in the Visual Cortex of Rhesus Monkeys.Neuroscience bulletin · 2026Article
- Interaction Between Near Work and Narrowband Light on Choroidal Thickness.Investigative ophthalmology & visual science · 2026Article
- The role of circadian rhythms in the pathogenesis of myopia.Frontiers in physiology · 2026Review
- Influence of time-of-day and light wavelengths on ocular responses to defocus.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Article
- Diurnal Variations in Anterior Segment Parameters in Different Grades of Patients With Keratoconus.Translational vision science & technology · 2025Article
- Influence of body position and time of day on ocular rhythms.Scientific reports · 2025Article
- Childhood Myopia Part II: Treatment Mechanisms, Emerging Options, and Considerations.Investigative ophthalmology & visual science · 2025Review
- Circadian Rhythms in Murine Ocular Tissues Including Sclera Are Affected by Neurobasal A Medium Preincubation and Mouse Strain, but Not Sex.Investigative ophthalmology & visual science · 2025Article
- Upright positioning facilitates the absorption of macular hole-related oedema.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Choroidal blood flow changes in central serous chorioretinopathy.Scientific reports · 2025Article
- Intra- and Inter-Observer Agreement of a Portable A-Scan Ultrasound Biometer in Sitting and Supine Positions and Validity Against an Optical Biometer.Clinical optometry · 2025Article
- Optic Nerve Head Morphology and Macula Ganglion Cell Inner Plexiform Layer Thickness in Axially Anisometropic Rhesus Monkeys.Investigative ophthalmology & visual science · 2024Article
- Effects of Acute Mental Stress on Choroidal Thickness.Bioengineering (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Purpose: To investigate diurnal variations in anterior and posterior segment biometry and assess differences between emmetropic and myopic adults. Methods: Healthy subjects (n = 42, 23-41 years old) underwent biometry and spectral-domain optical coherence tomography imaging (SD-OCT) every 4 hours for 24 hours. Subjects were in darkness from 11:00 PM to 7:00 AM. Central corneal thickness, corneal power, anterior chamber depth, lens thickness, vitreous chamber depth, and axial length were measured. Thicknesses of the total retina, photoreceptor outer segments + RPE, photoreceptor inner segments, and choroid over a 6-mm annulus were determined. Results: All parameters except anterior chamber depth demonstrated significant diurnal variations, with no refractive error differences. Amplitude of choroid diurnal variation correlated with axial length (P = 0.05). Amplitude of axial length variation (35.71 ± 19.40 μm) was in antiphase to choroid variation (25.65 ± 2.01 μm, P < 0.001). The central 1-mm retina underwent variation of 5.03 ± 0.23 μm with a peak at 12 hours (P < 0.001), whereas photoreceptor outer segment + RPE thickness peaked at 4 hours and inner segment thickness peaked at 16 hours. Diurnal variations in retina and choroid were observed in the 3- and 6-mm annuli. Conclusions: Diurnal rhythms in anterior and posterior segment biometry were observed over 24 hours in adults. Differences in baseline parameters were found between refractive error groups, and choroid diurnal variation correlated with axial length. The retina and choroid exhibited diurnal thickness variations in foveal and parafoveal regions.
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Registered trials
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