Evidence map›Paper›PMID 30372465›Full record

ArticlePloS one2018

HIV and syphilis testing preferences among men who have sex with men and among transgender women in Lima, Peru.

Claire C Bristow, Noah Kojima, Sung-Jae Lee, Segundo R Leon, Lourdes B Ramos, Kelika A Konda, Brandon Brown, Carlos F Caceres, Jeffrey D Klausner

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Policies towards elimination of congenital syphilis in Latin America and the Caribbean: a regional review.Revista panamericana de salud publica = Pan American journal of public health · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Claire C BristowDepartment of Medicine, University of California San Diego, La Jolla, CA, United States of America.ORCID 0000-0002-0680-1218
Noah KojimaDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States of America.ORCID 0000-0002-3667-9719
Sung-Jae LeeDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States of America.
Segundo R LeonSchool of Public Health, Universidad Peruana Cayetano Heredia, Lima, Peru.
Lourdes B RamosSchool of Public Health, Universidad Peruana Cayetano Heredia, Lima, Peru.
Kelika A KondaDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States of America.
Brandon BrownDepartment of Medicine, University of California Riverside, Riverside, CA, United States of America.
Carlos F CaceresSchool of Public Health, Universidad Peruana Cayetano Heredia, Lima, Peru.
Jeffrey D KlausnerDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States of America.
University of California, Los Angeles · USUniversidad Peruana Cayetano Heredia · PEUniversity of California, Riverside · USUniversity of California San Diego · US

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RAPHAEL J LANDOVITZ · 1997 to 2026
$53.5M
Virology CoreP30AI028697 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JAMIESON-KARAVODIN, BETH DEIRDRE · 1991 to 2018
$39.9M
University of California Launching Future Leaders in Global Health Research Training ProgramD43TW009343 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIG R COHEN, Sung-Jae Lee · 2017 to 2026
$14.7M
HOPE Training GrantT32AI007384 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Sara Gianella Weibel, Scott L Letendre · 1990 to 2026
$9.7M
Northern/Pacific Universities Global Health Research Training ConsortiumR25TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI KOLARS, JOSEPH C., NERURKAR, VIVEK RAMCHANDRA · 2012 to 2016
$5.9M
Syphilis: Translating technology to understand a neglected epidemicR01AI099727 · NIAID · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI CACERES, CARLOS F. · 2012 to 2016
$1.1M
Family-Focused HIV Disclosure Intervention in ThailandK01MH085503 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LEE, SUNG-JAE · 2009 to 2013
$755k
Molecular epidemiology of HIV and Neisseria gonorrhoeae in the context of drug resistanceK01AI136725 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BRISTOW, CLAIRE C · 2018 to 2022
$689k
FIC NIH HHS D43 TW009343FIC NIH HHS R25 TW009345NCATS NIH HHS UL1 TR000124NIAID NIH HHS K01 AI136725NIAID NIH HHS P30 AI028697NIAID NIH HHS R01 AI099727NIAID NIH HHS T32 AI007384NIMH NIH HHS K01 MH085503NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

backgroundMen who have sex with men (MSM) and transgender women in Peru are at high risk for acquiring syphilis and HIV infection. The World Health Organization highly recommends screening for HIV and syphilis to reduce morbidity and mortality associated with untreated infections. We aimed to identify factors associated with dual testing preferences for HIV and syphilis infection among MSM and transgender women in Lima, Peru.

methodsWe used conjoint analysis, an innovative method for systematically estimating consumer preferences. We created eight hypothetical test profiles varying across six dichotomous attributes: cost (free vs. $4), potential for false positive syphilis result (no false positive vs. some risk of false positive), time-to-result (20 minutes vs. 1 week), blood draw method (finger prick vs. venipuncture), test type (rapid vs. laboratory), and number of draws (1 vs. 2). We fit a conjoint analysis model for each participant using a simple main effects ANOVA. Attribute importance values were calculated using percentages from relative ranges in the attribute's utility values. Results were summarized across participants and averages were reported.

resultsWe recruited 415 MSM/transgender women over 18 years of age from two STD clinics in Lima, Peru. No potential for syphilis false positive result (no false positive vs. some potential for false positive) had the largest average impact on willingness to use the test and on average accounted for 23.8% of test type preference, followed by cost (free vs. ~USD$4; 21.6%), time to results (20 minutes vs. 1 week; 17.4%), number of blood draws (1 draw vs. 2 draws; 13.8%), method of blood draw (fingerprick vs. venipuncture; 13.7%), and test type (rapid POC vs. laboratory; 9.7%).

conclusionMSM/transgender women in Peru prioritized accuracy, cost, timeliness and number of blood draws for HIV and syphilis testing. Implementing a low cost, accurate, rapid and dual testing strategy for HIV and syphilis could improve screening uptake and accessibility of testing to accelerate time to treatment.

Indexed as

AdultFemaleHIV InfectionsHomosexuality, MaleHumansMaleMass ScreeningPatient PreferencePeruSurveys and QuestionnairesSyphilisTransgender PersonsYoung Adult

Identifiers

PMID30372465
PMCPMC6205634
OpenAlexW2898823129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.