Evidence map›Paper›PMID 30372131›Full record

ArticleNutrition and cancer2019

Associations of Nut Intakes with Incident Sporadic Colorectal Adenoma: A Pooled Case-Control Study.

Xin Yin, Roberd M Bostick

Abstract read
In one paragraph

Article in Nutrition and cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xin Yina Department of Epidemiology , Emory University , Atlanta , Georgia , USA.
Roberd M Bosticka Department of Epidemiology , Emory University , Atlanta , Georgia , USA.ORCID 0000-0001-8230-9519

Funding

COLON CANCER PREVENTION RESEARCH UNITP01CA050305 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI ELMER, PATRICIA J · 1990 to 1994
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DIET, CELL PROLIFERATION, AND COLON NEOPLASIA STUDYR01CA066539 · NCI · WAKE FOREST UNIVERSITY · PI BOSTICK, ROBERD · 1994 to 1996
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NCI NIH HHS P01 CA050305NCI NIH HHS R01 CA066539
6 · The paper itself

Abstract

introductionConsumption of nuts, which contain multiple anti-carcinogenic components, has been inversely associated with colorectal cancer (CRC), particularly among women, but has not been investigated in relation to colorectal adenoma, the immediate precursor to most CRCs.

methodsWe pooled data from three case-control studies of incident, sporadic colorectal adenoma (n = 785 cases, 2107 controls) in which dietary intakes were assessed using food frequency questionnaires, and analyzed the data using multivariable unconditional logistic regression.

resultsAmong men and women combined, the multivariable-adjusted odds ratios (OR) and 95% confidence intervals (CI) for the association of total nut product (all nuts and peanut butter combined) intakes, for those who consumed 0.5-1.5, 2.0-5.5, and ≥6 servings/week relative to no nut consumption were 0.81 (0.58, 1.12), 0.86 (0.61, 1.23), and 0.93 (0.65, 1.31), respectively. However, among women, the corresponding ORs and 95% CIs were 0.62 (0.40, 0.97), 0.57 (0.35, 0.94), and 0.78 (0.48, 1.25), respectively.

conclusionsThese results suggest that moderate nut consumption may be associated with lower risk for colorectal adenoma, primarily among women.

Indexed as

NutsAdenomaCase-Control StudiesColorectal NeoplasmsDietFemaleHumansIncidenceMaleMiddle AgedSurveys and QuestionnairesUnited States

Identifiers

PMID30372131
PMCPMC6488463

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.