ArticleAlcoholism, clinical and experimental research2019
What Is Addiction? How Can Animal and Human Research Be Used to Advance Research, Diagnosis, and Treatment of Alcohol and Other Substance Use Disorders?
Article in Alcoholism, clinical and experimental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Etiologic, Theory-Based, Ontogenetic Hierarchical Framework of Alcohol Use Disorder: A Translational Systematic Review of Reviews.Psychological bulletin · 2021Pooled it
- Revisiting the role of negative affect in alcohol use disorder: A longitudinal evaluation of Koob's allostatic model.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026Article
- "General Addiction Liability" Revisited.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- The Dopamine System in Mediating Alcohol Effects in Humans.Current topics in behavioral neurosciences · 2025Review
- The Effect of Cognitive Behavioral Therapy on Impulsivity in Addictive Disorders: a Narrative Review.Current addiction reports · 2023Article
- Peer-elicited alcohol craving in adolescents and emerging adults: Bridging the laboratory and natural environment.Alcohol, clinical & experimental research · 2023Article
- Proposing an integrative, dynamic and transdiagnostic model for addictions: dysregulation phenomena of the three main modes of the predostatic mind.Frontiers in psychiatry · 2023Article
- Cannabis Use Disorder: A Behavioral Economic Perspective.Current addiction reports · 2022Article
- Craving, stimulation, and sedation as predictors of alcohol demand under intoxication.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2022Article
- Incubation of alcohol craving as it naturally occurs in a developmentally diverse sample of dependent and nondependent drinkers.Addiction biology · 2021Article
- Mechanisms of Alcohol Addiction: Bridging Human and Animal Studies.Alcohol and alcoholism (Oxford, Oxfordshire) · 2020Review
- Using an Experimental Medicine Approach to Identify Novel Determinants of Addiction.Perspectives on behavior science · 2019Article
- Addiction Models and the Challenge of Having Impact.Alcoholism, clinical and experimental research · 2019Article
- Toward more efficient diagnostic criteria sets and rules: The use of optimization approaches in addiction science.Addictive behaviors · 2019Article
Corrections and comments
- Commented on by
Authors and funding
3 authors.
Funding
Abstract
The current article highlights key issues in defining, studying, and treating addiction, a concept related to but distinct from substance use disorders. The discussion is based upon a roundtable discussion at the 2017 annual meeting of the Research Society on Alcoholism where Warren K. Bickel and John C. Crabbe were charged with answering a range of questions posed by Kenneth J. Sher. All the presenters highlighted a number of central concerns for those interested in assessing and treating addiction as well as those seeking to conduct basic preclinical research that is amenable to meaningful translation to the human condition. In addition, the discussion illustrated both the power and limitations of using any single theory to explain multiple phenomena subsumed under the rubric of addiction. Among the major issues examined were the important differences between traditional diagnostic approaches and current concepts of addiction, the difficulty of modeling key aspects of human addiction in nonhuman animals, key aspects of addiction that have, to date, received little empirical attention, and the importance of thinking of recovery as a phenomenon that possibly involves processes distinct from those undergirding the development and maintenance of addiction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.