Evidence map›Paper›PMID 30371517›Full record

SynthesisThe Clinical journal of pain2019

Prognostic Factors for Physical Functioning After Multidisciplinary Rehabilitation in Patients With Chronic Musculoskeletal Pain: A Systematic Review and Meta-Analysis.

Elena Tseli, Katja Boersma, Britt-Marie Stålnacke, Paul Enthoven, Björn Gerdle, Björn O Äng, Wilhelmus J A Grooten

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Clinical journal of pain, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03882333 (Effects of Acute Exercise on Pain and Human Movement - a Randomised Controlled Study in Patients With Chronic Pain and Healthy Controls), which is not on this map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03882333 nacompletednot on this map

Effects of Acute Exercise on Pain and Human Movement - a Randomised Controlled Study in Patients With Chronic Pain and Healthy Controls

TypeinterventionalSponsorDalarna UniversityRan2018 to 2021Enrolled82ConditionsChronic Musculoskeletal Disease, Chronic Pain, WidespreadArmsAcute exercise
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Elena TseliDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet.
Katja BoersmaSchool of Law, Psychology and Social Work, Örebro University, Örebro.
Britt-Marie StålnackeDepartment of Community Medicine and Rehabilitation, Rehabilitation Medicine, Umeå University, Umeå.
Paul EnthovenDepartment of Medical and Health Sciences.
Björn GerdleDepartment of Medical and Health Sciences, Pain and Rehabilitation Centre, Linköping University, Linköping.
Björn O ÄngDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet.
Wilhelmus J A GrootenDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet.
Karolinska Institutet · SEKarolinska University Hospital · SELinköping University · SEÖrebro University · SEUppsala University · SE

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectivesThis systematic review aimed to identify and evaluate prognostic factors for long-term (≥6 mo) physical functioning in patients with chronic musculoskeletal pain following multidisciplinary rehabilitation (MDR). MATERIALS AND

methodsElectronic searches conducted in MEDLINE, PsycINFO, EMBASE, CINAHL, Web of Science, and Cochrane CENTRAL revealed 25 original research reports, published 1983-2016, (n=9436). Potential prognostic factors relating to initial pain and physical and psychological functioning were synthesized qualitatively and quantitatively in random effects meta-analyses. The level of evidence (LoE) was evaluated with Grading of Recommendations Assessment, Development and Evaluation (GRADE).

resultsPain-related factors (intensity and chronicity) were not associated with function/disability at long-term follow-up, odds ratio (OR)=0.84; 95% confidence interval (CI), 0.65-1.07 and OR=0.97; 95% CI, 0.93-1.00, respectively (moderate LoE). A better function at follow-up was predicted by Physical factors; higher levels of initial self-reported functioning, OR=1.07; 95% CI, 1.02-1.13 (low LoE), and Psychological factors; low initial levels of emotional distress, OR=0.77; 95% CI, 0.65-0.92, low levels of cognitive and behavioral risk factors, OR=0.85; 95% CI, 0.77-0.93 and high levels of protective cognitive and behavioral factors, OR=1.49; 95% CI, 1.17-1.90 (moderate LoE). DISCUSSION: While pain intensity and long-term chronicity did not predict physical functioning in chronic pain patients after MDR, poor pretreatment physical and psychological functioning influenced the prognosis negatively. Thus, treatment should further target and optimize these modifiable factors and an increased focus on positive, psychological protective factors may perhaps provide an opening for yet untapped clinical gains.

Indexed as

Chronic PainHumansMusculoskeletal PainPrognosis

Identifiers

PMID30371517
PMCPMC6343958
OpenAlexW2898111150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.