ArticleJournal of the American Heart Association2018
Long-Term Blood Pressure Level and Variability From Midlife to Later Life and Subsequent Cognitive Change: The ARIC Neurocognitive Study.
Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Association Between Blood Pressure Variability With Dementia and Cognitive Impairment: A Systematic Review and Meta-Analysis.Hypertension (Dallas, Tex. : 1979) · 2021Pooled it
- Blood pressure variability and cognitive dysfunction: A systematic review and meta-analysis of longitudinal cohort studies.Journal of clinical hypertension (Greenwich, Conn.) · 2021Pooled it
- Pooled it
- Visit-to-visit blood pressure variability and dementia risk after considering antihypertensive treatment: real-world data from the Japanese National Health Insurance.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Risk of Dementia and Its Associated Factors Among the Patients With Coronary Artery Disease Attending a Tertiary Cardiac Hospital of Dhaka City: A Cross-Sectional Study.Health science reports · 2025Article
- Blood Pressure and Cognitive Function in Older Adults.Clinics in geriatric medicine · 2024Review
- Risk factors for cognitive decline in non-demented elders with amyloid-beta positivity.Alzheimer's research & therapy · 2024Article
- Gray matter volume mediates the association of long-term blood pressure variability with cognitive function in an adult population.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Analysis of the relationship between blood pressure variability and subtle cognitive decline in older adults.World journal of psychiatry · 2023Article
- Year-by-Year Blood Pressure Variability From Midlife to Death and Lifetime Dementia Risk.JAMA network open · 2023Article
- Twenty-four-hour ambulatory blood pressure variability and association with ischemic stroke subtypes in the subacute stage.Frontiers in neurology · 2023Article
- High visit-to-visit blood pressure variability predicts global cognitive decline: The Multi-Ethnic Study of Atherosclerosis.Alzheimer's & dementia (New York, N. Y.) · 2022Article
- Heart health meets cognitive health: evidence on the role of blood pressure.The Lancet. Neurology · 2021Review
- Association between Blood Pressure, Blood Pressure Variability, and Post-Stroke Cognitive Impairment.Biomedicines · 2021Review
- Association of Liver Transaminase Levels and Long-Term Blood Pressure Variability in Military Young Males: The CHIEF Study.International journal of environmental research and public health · 2020Article
- Association of Cardiovascular Risk Factors with Cerebral Perfusion in Whites and African Americans.Journal of Alzheimer's disease : JAD · 2020Article
- Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study.The Lancet. Neurology · 2019Article
- Long-Term Blood Pressure Level and Variability From Midlife to Later Life and Subsequent Cognitive Change: The ARIC Neurocognitive Study.Journal of the American Heart Association · 2018Article
- Diastolic Blood Pressure and Cognitive Functioning: Differences by Systolic Blood Pressure Among US Adults.American journal of Alzheimer's disease and other dementiasArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Background To understand how blood pressure ( BP ) from midlife and beyond is related to cognition in older age, a lifespan approach is needed. We assessed the associations of BP levels and variability from midlife on with subsequent cognitive change. Methods and Results The ARIC (Atherosclerosis Risk in Communities) Study participants underwent 4 clinic BP measurements (visit 1, 2, 3, and 4 BP s) between 1987 and 1998, and their mean levels and average real variability ( ARV ) were assessed as exposures. A global cognitive z score, estimated from the Delayed Word Recall Test, Digit Symbol Substitution Test, and Word Fluency Test scores, was calculated at 1996 to 1998 (visit 4) and 2011 to 2013 (visit 5). Among 11 408 participants (mean age, 54 years; 56% women; 21% black race), mean systolic BP ( SBP )/diastolic BP ( DBP ) level was 123/72 mm Hg, and ARV
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.