ArticleJournal of the American Heart Association2018
Cognitive Impairment and Risk of All-Cause and Cardiovascular Disease Mortality Over 20-Year Follow-up: Results From the BLSA.
Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Perceptions and responses to cognitive decline in people with diabetes: A systematic review of qualitative studies.Frontiers in public health · 2023Pooled it
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- Review
- Association between cognitive function and all-cause mortality among US older adults with cardiovascular-kidney-metabolic syndrome.BMC geriatrics · 2026Article
- Article
- Associations between falls and other serious adverse events and antihypertensive medication in individuals with dementia: An observational cohort study.PLoS medicine · 2025Observational
- Longitudinal associations between medication use and phenotypic aging: insights from the Baltimore longitudinal study of aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Observational
- Association between healthy lifestyle and cognitive decline, all-cause mortality, and mortality from cardiovascular and cerebrovascular diseases: a 10-year population-based prospective cohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Impact of Combined Cognitive and Physical Impairments on Long-Term Prognosis in Elderly Cardiovascular Disease Patients: A Prospective Cohort Study.Clinical interventions in aging · 2025Article
- Combined association of gait speed and processing speed on cardiometabolic disease mortality risk in the US older adults: a prospective cohort study from NHANES.Frontiers in aging neuroscience · 2025Article
- The Risk of Atrial Fibrillation and Previous Ischemic Stroke in Cognitive Decline.Journal of clinical medicine · 2024Article
- Article
- Associations between modifiable risk factors and cognitive function in middle-aged and older Chinese adults: joint modelling of longitudinal and survival data.Frontiers in public health · 2024Article
- Article
- Association of cognitive impairment and diabetes on survival in Chinese older people with hypertension: a 10-year prospective study.BMC geriatrics · 2023Article
- The Positive Impact of Early Frailty Levels on Mortality in Elderly Patients with Severe Aortic Stenosis Undergoing Transcatheter/Surgical Aortic Valve Replacement.Journal of cardiovascular development and disease · 2023Article
- The Effect of Cognitive Impairment on the Association Between Social Network Properties and Mortality Among Older Korean Adults.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023Article
- Exploring the association between cognitive decline and all-cause mortality with blood pressure as a potential modifier in oldest old individuals.Scientific reports · 2022Article
- Montreal cognitive assessment (MoCA) is highly correlated with 1-year mortality in hip fracture patients.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Article
- Plant-based dietary patterns and cognitive function: A prospective cohort analysis of elderly individuals in China (2008-2018).Brain and behavior · 2022Article
Corrections and comments
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Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Cognitive impairment may increase the risk of all-cause and cardiovascular disease ( CVD ) mortality. This study examined the association between cognitive function and risk of all-cause and CVD mortality among the elderly in Beijing, China. Methods and Results A total of 1996 participants aged ≥55 years at baseline were enrolled from the BLSA (Beijing Longitudinal Study of Aging). Cognitive function was assessed using the Mini-Mental State Examination ( MMSE ), and participants were categorized as: <18, 18 to 23, 24 to 27, and 28 to 30. Cox proportional hazard models were used to estimate the association. Hazard ratio ( HR ) and 95% confidence interval ( CI ) were reported. During a 20-year follow-up, 1122 (56.21%) participants died, 478 (42.60%) of whom died of CVD . Compared with MMSE scores of 28 to 30, participants with MMSE scores of <18 were independently associated with all-cause mortality ( hazard ratio, 2.14; 95% confidence interval, 1.59-2.87; P<0.001) and CVD mortality (hazard ratio , 4.52; 95% confidence interval , 2.80-7.30, P<0.001). Each 5-point decrease in MMSE score was associated with a 34% increased risk of all-cause mortality and a 56% increased risk of CVD mortality. This relationship remained statistically significant after using the competing risk model to consider non- CVD death as a competing risk event. Conclusion Cognitive impairment measured by MMSE score was associated with elevated risk of all-cause and CVD mortality among the elderly in Beijing, China.
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