Evidence map›Paper›PMID 30371152›Full record

ArticleJournal of the American Heart Association2018

Early Use of Echocardiography in Patients With Acute Pulmonary Embolism: Findings From the RIETE Registry.

Behnood Bikdeli, José Luis Lobo, David Jiménez, Philip Green, Carmen Fernández-Capitán, Alessandra Bura-Riviere, Remedios Otero, Marco R DiTullio, Silvia Galindo, Martin Ellis and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

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  15. CHAClinical cardiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 20 institutions in 17 countries.

Behnood Bikdeli1 Division of Cardiology Department of Medicine Columbia University Medical Center/New York-Presbyterian Hospital New York NY.
José Luis Lobo3 Department of Pneumonology Hospital Universitario Araba Álava Spain.
David Jiménez4 Respiratory Department Hospital Ramón y Cajal Madrid Spain.
Philip Green1 Division of Cardiology Department of Medicine Columbia University Medical Center/New York-Presbyterian Hospital New York NY.
Carmen Fernández-Capitán6 Department of Internal Medicine Hospital Universitario La Paz Madrid Spain.
Alessandra Bura-Riviere7 Department of Vascular Medicine Hôpital de Rangueil Toulouse France.
Remedios Otero8 Department of Pneumonology Hospital Universitario Virgen del Rocío Seville Spain.
Marco R DiTullio1 Division of Cardiology Department of Medicine Columbia University Medical Center/New York-Presbyterian Hospital New York NY.
Silvia Galindo9 S&H Medical Sciences Services Madrid Spain.
Martin Ellis10 Department of Haematology Meir Hospital Kfar Saba Israel.
Sahil A Parikh1 Division of Cardiology Department of Medicine Columbia University Medical Center/New York-Presbyterian Hospital New York NY.
Manuel Monreal11 Hospital Universitari Germans Trias i Pujol Badalona, Barcelona Spain.
RIETE Investigators
Martinez VA Medical Center · USNewYork–Presbyterian Hospital · USUniversidad Dr. José Gregorio Hernández · VEBarron Associates (United States) · USAbili (Brazil) · BRAmada (Japan) · JPBüchi Labortechnik · CHCampo Arqueologico de Mertola · PTCasa de Velázquez · ESFoundation for Agronomic Research · USGhana Institute of Languages · GHHesco (United States) · USHospital Fernández · ARHospital General Universitario Morales Meseguer · ESInstituto Benjamin Constant · BRMarzano Research (United States) · USMazzoni Center · USMeir Medical Center · ILPace University · USSt. Laurent Institute · US

Funding

POSTDOCTORAL TRAINING IN CARDIOVASCULAR DISEASET32HL007854 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Marwah Abdalla, Michael Argenziano · 1996 to 2026
$14.7M
NHLBI NIH HHS T32 HL007854
6 · The paper itself

Abstract

Background Transthoracic echocardiography ( TTE ) is often considered for risk stratification of patients with acute pulmonary embolism ( PE ). We sought to determine the contemporary utilization of early TTE (within 72 hours of PE diagnosis) and explored the association between TTE findings and PE -related mortality. Methods and Results Data from the RIETE (Registro Informatizado Enfermedad TromboEmbolica) registry, a multicenter registry of consecutive patients with acute PE , were used (2001-July 2017). We used a generalized linear mixed model to determine predictors of early TTE performance. Moreover, the association between 3 TTE variables (right atrial enlargement, right ventricular hypokinesis, and presence of right heart thrombi) and 30-day PE -related mortality was assessed in generalized linear mixed models adjusted for PE severity index, and other comorbidities. Among 35 935 enrollees with acute PE , 15 375 (42.8%) underwent early TTE . There was an increase in early TTE utilization rate over time ( P<0.001 for trend). Younger age, female sex, enrollment in countries other than Spain, history of coronary disease, heart failure, atrial fibrillation, tachycardia, and hypotension were the main predictors of early TTE ( P<0.01 for all). In multivariable analyses, right atrial enlargement (adjusted odds ratio: 3.74; 95% confidence interval, 2.10-6.66), right ventricular hypokinesis (adjusted odds ratio: 3.11, 95% confidence interval: 1.85-5.21) and right heart thrombi (adjusted odds ratio: 4.39, 95% confidence interval, 1.99-9.71) were associated with increased odds for PE -related mortality. Conclusions Early TTE is commonly performed for acute PE and utilization rates have increased over time. Right atrial enlargement, right ventricular hypokinesis, and right heart thrombi are predictive of worse outcomes. Clinical Trial Registration URL : http://www.clinicaltrials.gov . Unique identifier: NCT 02832245.

Indexed as

Acute DiseaseAgedAged, 80 and overAge FactorsAtrial FibrillationCoronary DiseaseEchocardiographyFemaleHeart AtriaHeart DiseasesHeart FailureHumansHypotensionLinear ModelsMaleMiddle Agedechocardiographypulmonary embolismtrends

Identifiers

PMID30371152
PMCPMC6201438
OpenAlexW2888516392

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.