ArticleJournal of applied clinical medical physics2018
Re-irradiation volumetric modulated arc therapy optimization based on cumulative biologically effective dose objectives.
Article in Journal of applied clinical medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Treatment planning for lung cancer reirradiation accounting for previously delivered dose.Physics and imaging in radiation oncology · 2026Article
- A reirradiation workflow for managing patients with treatments planned in a multi-TPS environment.Technical innovations & patient support in radiation oncology · 2026Article
- Individualised dose mapping uncertainty estimation in the reirradiation setting.Physics and imaging in radiation oncology · 2025Article
- Reirradiation - still navigating uncharted waters?Clinical and translational radiation oncology · 2024Review
- Automated planning of stereotactic spine re-irradiation using cumulative dose limits.Physics and imaging in radiation oncology · 2024Article
- Review and recommendations on deformable image registration uncertainties for radiotherapy applications.Physics in medicine and biology · 2023Review
- Article
- Re-irradiation Using Stereotactic Radiotherapy: A Bibliometric Analysis of Research Trends.Cureus · 2023Review
- Adaptive sequential plan-on-plan optimization during prostate-specific antigen response guided radiotherapy of recurrent prostate cancer.Physics and imaging in radiation oncology · 2021Article
- The Special Medical Physics Consult Process for Reirradiation Patients.Advances in radiation oncologyArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this note is to introduce a clinical tool that generates ideal base plan dose distributions to enable re-irradiation volumetric modulated arc therapy (VMAT) optimization based on cumulative biological effective dose objectives for specific organs at risk (OARs). The tool is demonstrated with a lung cancer case that required re-irradiation at our clinic. First, previous treatment dose is deformed onto the retreatment computed tomography (CT) using commercial software. Then, the in-house Matlab tool alters the deformed previous dose using radiobiological concepts on a voxel-by-voxel manner to generate an ideal base plan dose distribution. Ideal base plans that were generated using the in-house Matlab tool were compatible with the Varian Eclipse™ treatment planning system. The tool enabled optimization of VMAT re-irradiation plans using cumulative dose limits for OARs and all OAR cumulative dose objectives were met on the first optimization for the recurrent lung cancer case tested.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.