Evidence map›Paper›PMID 30370497›Full record

ArticleInternational archives of occupational and environmental health2019

Prolonged or serious conflicts at work and incident dementia: a 23-year follow-up of the Copenhagen City Heart Study.

Kazi Ishtiak-Ahmed, Åse Marie Hansen, Erik Lykke Mortensen, Anne Helene Garde, Ane Nørgaard, Finn Gyntelberg, Naja Hulvej Rod, Sabrina Islamoska, Rikke Lund, Thien Kieu Thi Phung and 3 more

Open access · hybridAbstract read
In one paragraph

Article in International archives of occupational and environmental health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Is Stress an Overlooked Risk Factor for Dementia? A Systematic Review from a Lifespan Developmental Perspective.Prevention science : the official journal of the Society for Prevention Research · 2023
    Pooled it
  2. Multidimensional workplace stressors differentially impact cognitive trajectories.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Social determinants of dementia: A scoping review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Kazi Ishtiak-AhmedDepartment of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark. kaah@sund.ku.dk.ORCID http://orcid.org/0000-0003-3651-4612
Åse Marie HansenDepartment of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark.
Erik Lykke MortensenDepartment of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark.
Anne Helene GardeDepartment of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark.
Ane NørgaardDepartment of Neurology, Danish Dementia Research Centre, Rigshospitalet, University of Copenhagen Section 6911, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Finn GyntelbergThe National Research Centre for the Working Environment, Lersø Parkallé 105, 2100, Copenhagen, Denmark.
Naja Hulvej RodDepartment of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark.
Sabrina IslamoskaDepartment of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark.
Rikke LundDepartment of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark.
Thien Kieu Thi PhungCenter for Healthy Aging, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
Eva PrescottDepartment of Cardiology, Bispebjerg University Hospital, Bispebjerg Bakke 23, 2400, Copenhagen, Denmark.
Gunhild WaldemarDepartment of Neurology, Danish Dementia Research Centre, Rigshospitalet, University of Copenhagen Section 6911, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Kirsten Nabe-NielsenDepartment of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark.
University of Copenhagen · DKBispebjerg Hospital · DKNational Research Centre for the Working Environment · DK

Funding

The Danish Working Environment Research Fund 10-2015-03 20150017498
6 · The paper itself

Abstract

purposeOnly a few studies have investigated the impact of negative aspects of social relations on cognitive function, and they have shown mixed results. Conflicts at work are part of the negative aspects of social relations, but the impact of experiencing conflicts at work has not yet been investigated as a risk factor for dementia. Therefore, we investigated whether experiencing prolonged or serious conflicts with a supervisor or colleagues at work was associated with incident dementia in old age.

methodsWe analyzed data of 6,436 men and women from the third survey of the Copenhagen City Heart Study. At baseline in 1991-1994, the participants reported whether they had ever had a prolonged or serious conflict at work. The participants were followed until 2014. We used Poisson regression to estimate incidence rate ratios (IRR) and their 95% confidence intervals (CI).

resultsAfter adjusting for potential confounders, the IRR for dementia was 1.53 (95% CI 0.77-3.03) among participants who had reported having prolonged or serious conflicts both with a supervisor and colleagues compared with participants who had never had such conflicts. In separate analyses stratified by sex, the IRRs were 2.14 (95% Cl 0.97-4.71) for men and 0.98 (95% Cl 0.29-3.32) for women.

conclusionsOur findings did not support an overall association between experiencing prolonged or serious conflicts at work and incident dementia. However, because of the large differences in the point estimates for men and women, future research could aim at investigating potential sex differences regarding the association between conflicts at work and dementia.

Indexed as

Interpersonal RelationsAgedAged, 80 and overDementiaDenmarkFemaleFollow-Up StudiesHumansMaleMiddle AgedOccupational StressRisk FactorsSex FactorsStress, PsychologicalSurveys and QuestionnairesAlzheimer’sCohort studyMidlife risk factorsNegative aspects of social relationsPsychosocial work factorsSocial relations

Identifiers

PMID30370497
PMCPMC6341042
OpenAlexW2898181159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.