ArticleClinical research in cardiology : official journal of the German Cardiac Society2019
Diagnostic and prognostic value of plasma volume status at emergency department admission in dyspneic patients: results from the PARADISE cohort.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 42 citations in OpenAlex.
- Prognostic Significance of Estimated Plasma Volume Status in Patients with Heart Failure: A Systematic Review and Meta-Analysis.Acta Cardiologica Sinica · 2026Article
- The Impact of Meteorological Variables on Heart Failure Hospitalizations.JACC. Advances · 2025Article
- Nonlinear association between estimated plasma volume status and acute kidney injury in acute pancreatitis patients.World journal of gastroenterology · 2025Article
- Predictive value of blood urea nitrogen to creatinine ratio and estimated plasma volume status in heart failure.BMC cardiovascular disorders · 2025Article
- Estimated plasma volume status as a simple and accessible predictor of 28-day mortality in septic shock: insights from a retrospective study of the MIMIC-IV database.Frontiers in medicine · 2024Article
- Estimated plasma volume status as a prognostic marker in patients with lower extremity artery disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Mechanistic insights into chloride-related heart failure progression according to the plasma volume status.ESC heart failure · 2022Article
- Type III procollagen peptide level can indicate liver dysfunction associated with volume overload in acute heart failure.ESC heart failure · 2022Article
- Prognostic Value of Estimated Plasma Volume Status in Patients With Sepsis.Journal of Korean medical science · 2022Observational
- Impact of Estimated Plasma Volume Status on Mortality in Right Heart Failure Patients: A Retrospective Cohort Study in Indonesia.Global heart · 2022Article
- Deviations From the Ideal Plasma Volume and Isolated Tricuspid Valve Surgery-Paving the Way for New Risk Stratification Parameters.Frontiers in cardiovascular medicine · 2022Article
- Estimated plasma volume status (ePVS) is a predictor for acute myocardial infarction in-hospital mortality: analysis based on MIMIC-III database.BMC cardiovascular disorders · 2021Article
- Calculated Plasma Volume Status Is Associated With Mortality in Acute Respiratory Distress Syndrome.Critical care explorations · 2021Article
- Estimated plasma volume status in heart failure: clinical implications and future directions.Clinical research in cardiology : official journal of the German Cardiac Society · 2021Review
- Clinical impact of estimated plasma volume status and its additive effect with the GRACE risk score on in-hospital and long-term mortality for acute myocardial infarction.International journal of cardiology. Heart & vasculature · 2021Article
- A Combination of Chest Radiography and Estimated Plasma Volume May Predict In-Hospital Mortality in Acute Heart Failure.Frontiers in cardiovascular medicine · 2021Article
- The mystery of "missing" visits in an emergency cardiology department, in the era of COVID-19.; a time-series analysis in a tertiary Greek General Hospital.Clinical research in cardiology : official journal of the German Cardiac Society · 2020Observational
- Article
- Prognostic impact of plasma volume estimated from hemoglobin and hematocrit in heart failure with preserved ejection fraction.Clinical research in cardiology : official journal of the German Cardiac Society · 2020Article
- Ultrasound indices of congestion in patients with acute heart failure according to body mass index.Clinical research in cardiology : official journal of the German Cardiac Society · 2020Observational
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Authors and funding
16 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundSystemic congestion, evaluated by estimated plasma volume status (ePVS), is associated with in-hospital mortality in acute heart failure (AHF). However, the diagnostic and prognostic value of ePVS in patients with acute dyspnea has been insufficiently studied.
objectivesTo assess the association between the first ePVS calculated from blood samples on admission in the emergency department (ED) and discharge diagnosis of AHF and in-hospital mortality in patients admitted for acute dyspnea.
methodsThe study included 1369 patients admitted for dyspnea in the ED in 2015. ePVS was calculated from hematocrit and hemoglobin values at admission. Comparisons of baseline characteristics according to ePVS tertiles were carried out and then associations between ePVS and the two outcomes "AHF diagnosis" and "intra-hospital mortality" were assessed using a logistic regression model.
results36.6% had a BNP > 400 pg/mL and median ePVS was 4.58 dL/g [3.96-5.55]. Overall in-hospital mortality was 11.1% (n = 149). In multivariable analysis, the third ePVS tertile (> 5.12 dL/g) had a significantly increased risk of having AHF (OR = 1.64 [1.16-2.33], p = 0.005). In-hospital mortality rose across ePVS tertiles (8.4-13.8% p < 0.01). ePVS greater than the first or second tertile threshold (respectively, 4.17 dL/g and 5.12 dL/g) were both significantly associated with a higher risk of in-hospital mortality (OR for 2nd/3rd tertile = 2.06 [1.25-3.38], p = 0.004 and OR for 3rd tertile = 1.54 [1.01-2.36], p = 0.04).
conclusionHigher ePVS values determined from first blood sample at admission are associated with a higher probability of AHF and in-hospital mortality in patients admitted in the ED for acute dyspnea.
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