Evidence map›Paper›PMID 30370375›Full record

ArticleCell surface (Amsterdam, Netherlands)2018

Yeast species-specific, differential inhibition of β-1,3-glucan synthesis by poacic acid and caspofungin.

Keunsook K Lee, Karen Kubo, Jehan Abdelmoneim Abdelaziz, Iain Cunningham, Alessandra de Silva Dantas, Xiaolin Chen, Hiroki Okada, Yoshikazu Ohya, Neil A R Gow

Open access · hybridAbstract read
In one paragraph

Article in Cell surface (Amsterdam, Netherlands), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 53 citations in OpenAlex.

  1. Micafungin exposure drives multidrug resistance inbioRxiv : the preprint server for biology · 2026
    Article
  2. Surfactin-Induced β-(1,3)-Glucan Exposure inFoods (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Low-level direct currents eradicate multi-drug-resistantChemical engineering journal (Lausanne, Switzerland : 1996) · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Caspofungin resistance in Candida albicans: genetic factors and synergistic compounds for combination therapies.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Review
  15. Review
  16. Article
  17. Prospects for anti-Cell surface (Amsterdam, Netherlands) · 2021
    Review
  18. Article
  19. Article
  20. Portuguese honeys as antimicrobial agents againstJournal of traditional and complementary medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Keunsook K LeeThe Aberdeen Fungal Group, MRC Centre for Medical Mycology, School of Medicine, Medical Sciences & Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK.
Karen KuboDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan.
Jehan Abdelmoneim AbdelazizThe Aberdeen Fungal Group, MRC Centre for Medical Mycology, School of Medicine, Medical Sciences & Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK.
Iain CunninghamThe Aberdeen Fungal Group, MRC Centre for Medical Mycology, School of Medicine, Medical Sciences & Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK.
Alessandra de Silva DantasThe Aberdeen Fungal Group, MRC Centre for Medical Mycology, School of Medicine, Medical Sciences & Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK.
Xiaolin ChenDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan.
Hiroki OkadaDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan.
Yoshikazu OhyaDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan.
Neil A R GowThe Aberdeen Fungal Group, MRC Centre for Medical Mycology, School of Medicine, Medical Sciences & Nutrition, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK.
University of Aberdeen · GBNational Institute of Advanced Industrial Science and Technology · JPThe University of Tokyo · JP

Funding

Wellcome Trust 075470Wellcome Trust 086827Wellcome Trust 101873Wellcome Trust 200208
6 · The paper itself

Abstract

The rise of widespread antifungal resistance fuels the need to explore new classes of inhibitory molecules as potential novel inhibitors. Recently a plant natural product poacic acid (PA) was shown to inhibit β-1,3-glucan synthesis, and to have antifungal activity against a range of plant pathogens and against

Indexed as

Antifungal agentsCandida speciesFks1Fungal cell wallGlucan synthesis

Identifiers

PMID30370375
PMCPMC6195761
OpenAlexW2893145193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.