Evidence map›Paper›PMID 30370276›Full record

ReviewAnnals of translational medicine2018

Heart-lung interactions during mechanical ventilation: the basics.

Syed S Mahmood, Michael R Pinsky

2 registry-linked trialsOpen access · hybridAbstract readReview
In one paragraph

Review in Annals of translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 108 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 3 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06123039 completednot on this mapstarted 2023, after this paper: background citation

Use of Heart-lung Interaction Parameters to Predict Haemodynamic Tolerance to the Open Lung Approach With Individualised PEEP During Invasive Mechanical Ventilation in the Operating Room

TypeobservationalSponsorHospital Universitario La FeRan2023 to 2025Enrolled72ConditionsAnesthesia, Perioperative/Postoperative Complications, Hypovolemia, Haemodynamic InstabilityArmsTidal Volume Challenge, Recruitment maneuver obtaining individualised PEEP
NCT06812949 active not recruitingnot on this mapstarted 2025, after this paper: background citation

Echocardiographic Right Ventricular Evaluation in Assessment of ARDS Lung Recruitment (ECHO-REVEAL)

Typeobservational_patient_registrySponsorUniversity of BariRan2025 to 2026Enrolled60ConditionsARDSArmsPEEP Titration with Echocardiographic, Hemodynamic, and Ventilatory Measurements
3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 3 syntheses or guidelines pooled it, 211 citations in OpenAlex.

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  6. Vascular remodeling in asthma: from mechanisms to precision medicine.Current opinion in allergy and clinical immunology · 2026
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48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Syed S MahmoodDepartment of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Michael R PinskyDepartment of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
University of Pittsburgh · US

Funding

Predicting Patient Instability Noninvasively for Nursing Care-Two (PPINNC-2)R01NR013912 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AL-ZAITI, SALAH S, CLERMONT, GILLES · 2012 to 2025
$7.0M
Multidisciplinary Training in Critical Care Outcomes ResearchT32HL007820 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Timothy D Girard, Jeremy M Kahn · 1996 to 2026
$6.4M
NHLBI NIH HHS T32 HL007820NINR NIH HHS R01 NR013912
6 · The paper itself

Abstract

The hemodynamic effects of mechanical ventilation can be grouped into three clinically relevant concepts. First, since spontaneous ventilation is exercise. In patients increased work of breathing, initiation of mechanical ventilatory support may improve O

Indexed as

Afterloadheart-lung interactionspreloadventricular interdependence

Identifiers

PMID30370276
PMCPMC6186561
OpenAlexW2801671927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.