Evidence map›Paper›PMID 30370192›Full record

ArticleBioscience of microbiota, food and health2018

Effect of

Takuou Takimoto, Misaki Hatanaka, Tomohiro Hoshino, Tsuyoshi Takara, Ko Tanaka, Atsushi Shimizu, Hiroto Morita, Teppei Nakamura

Abstract read
In one paragraph

Article in Bioscience of microbiota, food and health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. Probiotic Supplementation and Bone Health Parameters in Adults: A Systematic Review and Meta-Analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Pooled it
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  4. A systematic review and meta-analysis of the effects of probiotics on bone outcomes in rodent models.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Pooled it
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  9. Systematic review and meta-analysis of the association between dairy consumption and the risk of hip fracture: critical interpretation of the currently available evidence.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Pooled it
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  16. Links between bone fractures and the gut microbiota.Nature reviews. Endocrinology · 2026
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33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Takuou TakimotoDepartment of Microbiological Flora Technology, Core Technology Laboratories, Asahi Group Holdings, Ltd., 11-10-5 Fuchinobe, Sagamihara, Kanagawa 252-0206, Japan.
Misaki HatanakaDepartment of Microbiological Flora Technology, Core Technology Laboratories, Asahi Group Holdings, Ltd., 11-10-5 Fuchinobe, Sagamihara, Kanagawa 252-0206, Japan.
Tomohiro HoshinoR&D Department, Orthomedico Inc., 1-4-1 Koishikawa, Bunkyo-ku, Tokyo, Japan.
Tsuyoshi TakaraTakara Clinic, Medical Corporation Seishinkai, Shinagawa-ku, Tokyo, Japan.
Ko TanakaTanaka Gastrointestinal Clinic, Shizuoka, Japan.
Atsushi ShimizuShimizu Gynecology Clinic, Shizuoka, Japan.
Hiroto MoritaDepartment of Microbiological Flora Technology, Core Technology Laboratories, Asahi Group Holdings, Ltd., 11-10-5 Fuchinobe, Sagamihara, Kanagawa 252-0206, Japan.
Teppei NakamuraDepartment of Microbiological Flora Technology, Core Technology Laboratories, Asahi Group Holdings, Ltd., 11-10-5 Fuchinobe, Sagamihara, Kanagawa 252-0206, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbiota influence the host immune system and are associated with various diseases. In recent years, postmenopausal bone loss has been suggested to be related to gut microbiota. In the present study, we investigated the treatment effect of the probiotic

Indexed as

bonemicrobiotaosteoporosisprobiotics

Identifiers

PMID30370192
PMCPMC6200670

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.