Evidence map›Paper›PMID 30370044›Full record

ArticleParkinson's disease2018

Potential Therapeutic Drugs for Parkinson's Disease Based on Data Mining and Bioinformatics Analysis.

Chuan Xu, Jiajun Chen, Xia Xu, Yingyu Zhang, Jia Li

Open access · goldAbstract read
In one paragraph

Article in Parkinson's disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chuan XuDepartment of Neurology (III), China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin, China.
Jiajun ChenDepartment of Neurology (III), China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin, China.
Xia XuYiwu Maternal and Child Health Hospital, Yiwu 322000, Zhejiang, China.
Yingyu ZhangDepartment of Neurology (III), China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin, China.
Jia LiDepartment of Neurology (III), China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin, China.ORCID 0000-0002-3422-2125
Jilin University · CNYiwu Science and Technology Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective is to search potential therapeutic drugs for Parkinson's disease based on data mining and bioinformatics analysis and providing new ideas for research studies on "new application of conventional drugs." Method differential gene candidates were obtained based on data mining of genes of PD brain tissue, original gene data analysis, differential gene crossover, pathway enrichment analysis, and protein interaction, and potential therapeutic drugs for Parkinson's disease were obtained through drug-gene relationship.

Identifiers

PMID30370044
PMCPMC6189653
OpenAlexW2894587079

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.