Evidence map›Paper›PMID 30369865›Full record

ArticleFrontiers in neuroscience2018

Ccl5 Mediates Proper Wiring of Feedforward and Lateral Inhibition Pathways in the Inner Retina.

D'Anne S Duncan, Rebecca L Weiner, Carl Weitlauf, Michael L Risner, Abigail L Roux, Emily R Sanford, Cathryn R Formichella, Rebecca M Sappington

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  4. Article
  5. Chemokine CCL5 promotes robust optic nerve regeneration and mediates many of the effects of CNTF gene therapy.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

D'Anne S DuncanVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, United States.
Rebecca L WeinerDepartment of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, United States.
Carl WeitlaufVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, United States.
Michael L RisnerVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, United States.
Abigail L RouxVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, United States.
Emily R SanfordVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, United States.
Cathryn R FormichellaVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, United States.
Rebecca M SappingtonVanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, United States.
Vanderbilt University Medical Center · USVanderbilt University · US

Funding

Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6M
TRAINING IN PHARMACOLOGICAL SCIENCEST32GM007628 · NIGMS · VANDERBILT UNIVERSITY · PI BARNETT, JOEY VICTOR, KAVALALI, EGE T · 1985 to 2022
$11.2M
Interleukin-6 and Retinal Ganglion Cell Degeneration in GlaucomaR01EY020496 · NEI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SAPPINGTON, REBECCA M · 2010 to 2020
$4.0M
Mapping Brain Activity with High Spatiotemporal Resolution using Graphene ProbesR01EY027729 · NEI · VANDERBILT UNIVERSITY · PI LI, DEYU · 2017 to 2021
$2.0M
NEI NIH HHS P30 EY008126NEI NIH HHS R01 EY020496NEI NIH HHS R01 EY027729NIGMS NIH HHS T32 GM007628
6 · The paper itself

Abstract

The β-chemokine Ccl5 and its receptors are constitutively expressed in neurons of the murine inner retina. Here, we examined the functional and structural significance of this constitutive Ccl5 signaling on retinal development. We compared outcomes of electrophysiology, ocular imaging and retinal morphology in wild-type mice (WT) and mice with Ccl5 deficiency (

Indexed as

amacrine cellbipolar cellCcl5chemokinegustducinPKCαretinal ganglion cell

Identifiers

PMID30369865
PMCPMC6194164
OpenAlexW2906176950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.