Evidence map›Paper›PMID 30369798›Full record

ArticleEuropean journal of dentistry

The anti-inflammatory effect of the platelet-rich plasma in the periodontal pocket.

Lubaba A Abdul Ameer, Zainab J Raheem, Saif Saadedeen Abdulrazaq, Basima Gh Ali, Maysaa Mahdi Nasser, Azza Wala Aldeen Khairi

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04082949 (Evaluation of Clinical Effects of Autologous Fibrin Glue Application as an Adjunct to Nonsurgical Periodontal Treatment of Chronic Periodontitis), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04082949 early_phase1completednot on this map

Evaluation of Clinical Effects of Autologous Fibrin Glue Application as an Adjunct to Nonsurgical Periodontal Treatment of Chronic Periodontitis

TypeinterventionalSponsorInonu UniversityRan2018 to 2019Enrolled18ConditionsChronic Periodontitis, Periodontal Pocket, Periodontal Attachment Loss, Periodontal DiseasesArmsautologous fibrin glue application as an adjunct to nonsurgical periodontal treatment of chronic periodontitis, placebo application as an adjunct to nonsurgical periodontal treatment of chronic periodontitis
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. PRP and PRF-Subgroups and Divisions When Used in Dentistry.Journal of personalized medicine · 2021
    Review
  14. Article
  15. Article
  16. Challenges of Engineering Biomimetic Dental and Paradental Tissues.Tissue engineering and regenerative medicine · 2020
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lubaba A Abdul AmeerDepartment of Periodontics, College of Dentistry, University of Baghdad, Baghdad, Iraq.
Zainab J RaheemDepartment of Periodontics, College of Dentistry, University of Baghdad, Baghdad, Iraq.
Saif Saadedeen AbdulrazaqDepartment of Oral and Maxillofacial Surgery, College of Dentistry, University of Baghdad, Baghdad, Iraq.
Basima Gh AliDepartment of Periodontics, College of Dentistry, University of Baghdad, Baghdad, Iraq.
Maysaa Mahdi NasserAL-Sader Dental Specialized Center, Baghdad, Iraq.
Azza Wala Aldeen KhairiDepartment of Periodontics, College of Dentistry, University of Baghdad, Baghdad, Iraq.
University of Baghdad · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveChronic periodontitis (CP) is a common inflammatory disease that causes destruction to the supporting tissues of the teeth. Many treatment modalities tried to stop the disease progression. Platelet-rich plasma (PRP) is one of the regenerative methods that used in adjunct to conventional periodontal treatment. The aim of this study was to evaluate the anti-inflammatory effect of PRP by monitoring the lymphocyte count before and after its application to the periodontal pocket. MATERIALS AND

methodsTwenty patients, with CP and a pocket depth equal to or deeper than 4 mm, subjected to scaling, root planing, and PRP injection into the pocket. The lymphocyte count measured before and after 1 month from PRP application. Clinical periodontal parameters were taken during two visits (1 month apart), with customized stent fabrication.

resultsAll clinical periodontal parameters showed a reduction in their value following 1 month of PRP application. There was a noticeable reduction in lymphocyte count from (mean 2.47 ± 0.91) to (mean 1.94 ± 0.77).

conclusionIn addition to its traditional uses, PRP has a great role in the periodontal treatment by its anti-inflammatory effect.

Indexed as

Lymphocyte countperiodontal pocketplatelet-rich plasma

Identifiers

PMID30369798
PMCPMC6178670
OpenAlexW2895739239

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.