Evidence map›Paper›PMID 30369733›Full record

ArticleIndian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion2018

A Low Incidence of Cytomegalo Virus Infection Following Allogeneic Hematopoietic Stem Cell Transplantation Despite a High Seroprevalence.

Anup J Devasia, Shoba Mammen, Anu Korula, Aby Abraham, N A Fouzia, Kavitha M Lakshmi, Asha Mary Abraham, Alok Srivastava, Vikram Mathews, Biju George

Abstract read
In one paragraph

Article in Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Highlights of Abstracts on Hematopoietic Stem Cell Transplant in Annual Conference of ISHBT 2018.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anup J Devasia1Department of Clinical Hematology, Christian Medical College, Vellore, India.
Shoba Mammen2Department of Clinical Virology, Christian Medical College, Vellore, India.
Anu Korula1Department of Clinical Hematology, Christian Medical College, Vellore, India.
Aby Abraham1Department of Clinical Hematology, Christian Medical College, Vellore, India.
N A Fouzia1Department of Clinical Hematology, Christian Medical College, Vellore, India.
Kavitha M Lakshmi1Department of Clinical Hematology, Christian Medical College, Vellore, India.
Asha Mary Abraham2Department of Clinical Virology, Christian Medical College, Vellore, India.
Alok Srivastava1Department of Clinical Hematology, Christian Medical College, Vellore, India.
Vikram Mathews1Department of Clinical Hematology, Christian Medical College, Vellore, India.
Biju George1Department of Clinical Hematology, Christian Medical College, Vellore, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytomegalovirus (CMV) infection remains an important cause of morbidity and mortality following allogeneic stem cell transplantation (SCT). We wanted to study if the high sero-prevalence seen in our population translated into a high incidence of CMV infection following SCT. This is a retrospective analysis of patients who underwent allogeneic SCT between January 2008 and December 2012 at our centre. 475 patients underwent allogeneic SCT for malignant (46.5%) and non-malignant (53.5%) haematological disorders. 463 (97.4%) SCT recipients and 403 (84.8%) SCT donors were IgG seropositive for CMV. CMV reactivation within 100 days post SCT was seen in 174 (36.6%) at a median of 41 days (range 10-100) post SCT. Ganciclovir was used in 166 patients (95.4%) for a mean duration of 16 days (range 5-32). 157 patients (90%) responded to therapy. Sixty-six patients (42.3%) had secondary reactivation of the virus. Use of a male donor (

Indexed as

Cytomegalo virusSeroprevalenceStem cell transplantation

Identifiers

PMID30369733
PMCPMC6186215

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