Evidence map›Paper›PMID 30369585›Full record

ArticleThe Journal of veterinary medical science2018

Intravenous human endothelial progenitor cell administration into aged mice enhances embryo development and oocyte quality by reducing inflammation, endoplasmic reticulum stress and apoptosis.

Geon A Kim, Yeonjae Lee, Hyun Jin Kim, Hyun Ju Oh, Sung Keun Kang, Jeong Chan Ra, Byeong Chun Lee

Open access · diamondAbstract read
In one paragraph

Article in The Journal of veterinary medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
  5. Research progress in proteasome inhibitor resistance to multiple myeloma.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Geon A KimDepartment of Theriogenology and Biotechnology, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
Yeonjae LeeHankuk Academy of Foreign Studies, Yongin-si, Gyeonggi-do 17035, Republic of Korea.
Hyun Jin KimSeoul National University, Seoul 08826, Republic of Korea.
Hyun Ju OhDepartment of Theriogenology and Biotechnology, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
Sung Keun KangBiostar Stem Cell Research Institute, R Bio Co., Ltd., Seoul 08506, Republic of Korea.
Jeong Chan RaBiostar Stem Cell Research Institute, R Bio Co., Ltd., Seoul 08506, Republic of Korea.
Byeong Chun LeeDepartment of Theriogenology and Biotechnology, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
Seoul National University · KRCell Biotech (South Korea) · KRHankuk University of Foreign Studies · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cell therapy has been proposed to restore the function and structure of injured tissues. In the present study, we investigated the ability of human endothelial progenitor cells (hEPCs) to attenuate ovarian aging and dysfunction. Female ICR mice aged 4 and 6 months were injected with cultured hEPCs. Cultured hEPCs were injected intravenously twice with 5 × 10

Indexed as

AgingApoptosisEmbryonic DevelopmentEndoplasmic Reticulum StressAnimalsCells, CulturedCytokinesEndothelial Progenitor CellsFemaleFertilityGene ExpressionHumansInflammationInflammation MediatorsMiceMice, Inbred ICRCytokinesInflammation Mediatorsendoplasmic reticulum stresshuman endothelial progenitor cellsinflammationovarian aging

Identifiers

PMID30369585
PMCPMC6305508
OpenAlexW2898603140

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.