Evidence map›Paper›PMID 30369486›Full record

ArticleJournal of lipid research2018

Oleoylethanolamide differentially regulates glycerolipid synthesis and lipoprotein secretion in intestine and liver.

Xiaoyue Pan, Gary J Schwartz, M Mahmood Hussain

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Xiaoyue PanDepartment of Cell Biology, State University of New York Downstate Medical Center, Brooklyn, NY Mahmood.hussain@nyulangone.org Xiaoyue.Pan@nyulangone.org.
Gary J SchwartzDepartments of Medicine and Neuroscience, Albert Einstein College of Medicine, Bronx, NY.
M Mahmood HussainDepartment of Cell Biology, State University of New York Downstate Medical Center, Brooklyn, NY Mahmood.hussain@nyulangone.org Xiaoyue.Pan@nyulangone.org.
Albert Einstein College of Medicine · USSUNY Downstate Health Sciences University · USVA NY Harbor Healthcare System · US

Funding

RESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0M
MOLECULAR MECHANISMS OF CHYLOMICRON ASSEMBLYR01DK046900 · NIDDK · SUNY DOWNSTATE MEDICAL CENTER · PI HUSSAIN, M MAHMOOD · 2001 to 2011
$3.0M
Avoiding toxicity associated with MTP ablationR01HL095924 · NHLBI · SUNY DOWNSTATE MEDICAL CENTER · PI HUSSAIN, M MAHMOOD · 2010 to 2013
$1.9M
Effects of miR-30c deficiency on plasma cholesterol and atherosclerosisR01HL137202 · NHLBI · NYU WINTHROP HOSPITAL · PI HUSSAIN, M MAHMOOD · 2017 to 2020
$1.5M
Circadian Regulation of AtherosclerosisR56HL137912 · NHLBI · NYU WINTHROP HOSPITAL · PI PAN, XIAOYUE · 2017 to 2017
$384k
Molecular mechanisms of chylomicron assemblyR56DK046900 · NIDDK · SUNY DOWNSTATE MEDICAL CENTER · PI HUSSAIN, M MAHMOOD · 2015 to 2015
$140k
ASSEMBLY OF APOB48 CONTAINING LIPOPROTEINSR29DK046900 · NIDDK · MCP HAHNEMANN UNIVERSITY · PI HUSSAIN, M MAHMOOD · 1995 to 1999
–
Regulation of plasma lipids and atherosclerosis by miR-30cI01BX001728 · VA · VA NEW YORK HARBOR HLTHCARE/SYS/BROOKLYN · PI HUSSAIN, M MAHMOOD · 2013 to 2016
–
BLRD VA I01 BX001728NHLBI NIH HHS R01 HL095924NHLBI NIH HHS R01 HL137202NHLBI NIH HHS R56 HL137912NIDDK NIH HHS P30 DK026687NIDDK NIH HHS R01 DK046900NIDDK NIH HHS R29 DK046900NIDDK NIH HHS R56 DK046900
6 · The paper itself

Abstract

Dietary fat absorption takes place in the intestine, and the liver mobilizes endogenous fat to other tissues by synthesizing lipoproteins that require apoB and microsomal triglyceride transfer protein (MTP). Dietary fat triggers the synthesis of oleoylethanolamide (OEA), a regulatory fatty acid that signals satiety to reduce food intake mainly by enhancing neural PPARα activity, in enterocytes. We explored OEA's roles in the assembly of lipoproteins in WT and

Indexed as

AnimalsCaco-2 CellsCarrier ProteinsCell Line, TumorCholesterol, VLDLDietary FatsEndocannabinoidsEnterocytesHepatocytesHep G2 CellsHumansIntestinesLipid MetabolismLipoproteinsLiverMiceCarrier ProteinsCholesterol, VLDLDietary FatsEndocannabinoidsLipoproteinsmicrosomal triglyceride transfer proteinOleic AcidsoleoylethanolamidePPAR alphaapolipoprotein Bchylomicronsmicrosomal triglyceride transfer proteinoleic acidperoxisome proliferator-activated receptor alphavery low density lipoprotein

Identifiers

PMID30369486
PMCPMC6277166
OpenAlexW2898757979

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.