Evidence map›Paper›PMID 30369107›Full record

ArticleJournal of biomedical optics2018

Integrated optical coherence tomography and multielement ultrasound transducer probe for shear wave elasticity imaging of moving tissues.

Andrei B Karpiouk, Donald J VanderLaan, Kirill V Larin, Stanislav Y Emelianov

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026
    Review
  2. Article
  3. Article
  4. Biomedical optics express · 2024
    Article
  5. Introduction to optical coherence elastography: tutorial.Journal of the Optical Society of America. A, Optics, image science, and vision · 2022
    Article
  6. Article
  7. Assessing colitisQuantitative imaging in medicine and surgery · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrei B KarpioukGeorgia Institute of Technology, Electrical and Computer Engineering Department, Atlanta, Georgia, United States.
Donald J VanderLaanGeorgia Institute of Technology, Electrical and Computer Engineering Department, Atlanta, Georgia, United States.
Kirill V LarinUniversity of Houston, Biomedical Engineering Department, Houston, Texas, United States.
Stanislav Y EmelianovGeorgia Institute of Technology, Electrical and Computer Engineering Department, Atlanta, Georgia, United States.

Funding

Optical Coherence Elastography of the CorneaR01EY022362 · NEI · UNIVERSITY OF HOUSTON · PI Salavat R Aglyamov, Kirill V Larin · 2012 to 2026
$6.7M
Optical elastography for assessment of myocardial regenerationR01HL130804 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI LARIN, KIRILL V, MARTIN, JAMES F · 2016 to 2019
$2.9M
NEI NIH HHS R01 EY022362NHLBI NIH HHS R01 HL130804
6 · The paper itself

Abstract

Accurate measurements of microelastic properties of soft tissues in-vivo using optical coherence elastography can be affected by motion artifacts caused by cardiac and respiratory cycles. This problem can be overcome using a multielement ultrasound transducer probe where each ultrasound transducer is capable of generating acoustic radiation force (ARF) and, therefore, creating shear waves in tissue. These shear waves, produced during the phase of cardiac and respiratory cycles when tissues are effectively stationary, are detected at the same observation point using phase-sensitive optical coherence tomography (psOCT). Given the known distance between the ultrasound transducers, the speed of shear wave propagation can be calculated by measuring the difference between arrival times of shear waves. The combined multitransducer ARF/psOCT probe has been designed and tested in phantoms and ex-vivo studies using fresh rabbit heart. The measured values of shear moduli are in good agreement with those reported in literature. Our results suggest that the developed multitransducer ARF/psOCT probe can be useful for many in-vivo applications, including quantifying the microelasticity of cardiac muscle.

Indexed as

Elasticity Imaging TechniquesTomography, Optical CoherenceAnimalsHeartImage Processing, Computer-AssistedPhantoms, ImagingRabbitsReproducibility of ResultsTransducersacoustic radiation forcecardiac musclemultielement ultrasound transducer probeoptical coherence tomography and elastographyshear wave elasticity imaging

Identifiers

PMID30369107
PMCPMC6210783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.