Evidence map›Paper›PMID 30369058›Full record

ArticleMicrobial biotechnology2019

Engineering bacteria for biogenic synthesis of chalcogenide nanomaterials.

Prithiviraj Chellamuthu, Frances Tran, Kalinga Pavan T Silva, Marko S Chavez, Mohamed Y El-Naggar, James Q Boedicker

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Synthesis of Palladium Nanoparticles by Electrode-RespiringACS biomaterials science & engineering · 2025
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Biosynthesis of Nanomaterials byFrontiers in microbiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Prithiviraj ChellamuthuDepartment of Physics and Astronomy, University of Southern California, Los Angeles, CA, USA.
Frances TranDepartment of Physics and Astronomy, University of Southern California, Los Angeles, CA, USA.
Kalinga Pavan T SilvaDepartment of Physics and Astronomy, University of Southern California, Los Angeles, CA, USA.
Marko S ChavezDepartment of Physics and Astronomy, University of Southern California, Los Angeles, CA, USA.
Mohamed Y El-NaggarDepartment of Physics and Astronomy, University of Southern California, Los Angeles, CA, USA.
James Q BoedickerDepartment of Physics and Astronomy, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0003-4107-3719
University of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbes naturally build nanoscale structures, including structures assembled from inorganic materials. Here, we combine the natural capabilities of microbes with engineered genetic control circuits to demonstrate the ability to control biological synthesis of chalcogenide nanomaterials in a heterologous host. We transferred reductase genes from both Shewanella sp. ANA-3 and Salmonella enterica serovar Typhimurium into a heterologous host (Escherichia coli) and examined the mechanisms that regulate the properties of biogenic nanomaterials. Expression of arsenate reductase genes and thiosulfate reductase genes in E. coli resulted in the synthesis of arsenic sulfide nanomaterials. In addition to processing the starting materials via redox enzymes, cellular components also nucleated the formation of arsenic sulfide nanomaterials. The shape of the nanomaterial was influenced by the bacterial culture, with the synthetic E. coli strain producing nanospheres and conditioned media or cultures of wild-type Shewanella sp. producing nanofibres. The diameter of these nanofibres also depended on the biological context of synthesis. These results demonstrate the potential for biogenic synthesis of nanomaterials with controlled properties by combining the natural capabilities of wild microbes with the tools from synthetic biology.

Indexed as

NanostructuresArsenicalsCloning, MolecularEscherichia coliGene ExpressionMetabolic EngineeringOxidoreductasesRecombinant ProteinsSalmonella typhimuriumShewanellaSulfidesArsenicalsarsenic trisulfideOxidoreductasesRecombinant ProteinsSulfides

Identifiers

PMID30369058
PMCPMC6302716
OpenAlexW2949279034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.