ArticleHuman brain mapping2019
Data-driven approaches for tau-PET imaging biomarkers in Alzheimer's disease.
Article in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The hippocampal sparing subtype of Alzheimer's disease assessed in neuropathology and in vivo tau positron emission tomography: a systematic review.Acta neuropathologica communications · 2022Pooled it
- Implication of the thalamus in sleep alterations observed in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Common and rare variant analyses implicateNPJ dementia · 2026Article
- Integrating imaging and omics for enhanced subtyping of mild cognitive impairment associated with Alzheimer's disease.Journal of translational medicine · 2025Article
- Genome-wide scan of Flortaucipir PET levels findsmedRxiv : the preprint server for health sciences · 2024Article
- Data-driven decomposition and staging of flortaucipir uptake in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Characterization of tau propagation pattern and cascading hypometabolism from functional connectivity in Alzheimer's disease.Human brain mapping · 2024Article
- A novel method for PET connectomics guided by fibre-tracking MRI: Application to Alzheimer's disease.Human brain mapping · 2024Article
- Alzheimer's disease: a review on the current trends of the effective diagnosis and therapeutics.Frontiers in aging neuroscience · 2024Review
- Multimodal subtypes identified in Alzheimer's Disease Neuroimaging Initiative participants by missing-data-enabled subtype and stage inference.Brain communications · 2024Article
- Early tau detection in flortaucipir images: validation in autopsy-confirmed data and implications for disease progression.Alzheimer's research & therapy · 2023Article
- Segmentation of Dynamic Total-Body [International journal of biomedical imaging · 2023Article
- Neuropsychological Performance Is Correlated With Tau Protein Deposition and Glucose Metabolism in Patients With Alzheimer's Disease.Frontiers in aging neuroscience · 2022Article
- Tau Biomarkers in Dementia: Positron Emission Tomography Radiopharmaceuticals in Tauopathy Assessment and Future Perspective.International journal of molecular sciences · 2021Review
- Indication of retrograde tau spreading along Braak stages and functional connectivity pathways.European journal of nuclear medicine and molecular imaging · 2021Article
- A multicenter comparison of [European journal of nuclear medicine and molecular imaging · 2021Article
- Clinical validity of increased cortical uptake of [European journal of nuclear medicine and molecular imaging · 2021Review
- Differential associations of APOE-ε2 and APOE-ε4 alleles with PET-measured amyloid-β and tau deposition in older individuals without dementia.European journal of nuclear medicine and molecular imaging · 2021Article
- Four distinct trajectories of tau deposition identified in Alzheimer's disease.Nature medicine · 2021Article
- Recent Advances in Imaging of Preclinical, Sporadic, and Autosomal Dominant Alzheimer's Disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021Review
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
Previous positron emission tomography (PET) studies have quantified filamentous tau pathology using regions-of-interest (ROIs) based on observations of the topographical distribution of neurofibrillary tangles in post-mortem tissue. However, such approaches may not take full advantage of information contained in neuroimaging data. The present study employs an unsupervised data-driven method to identify spatial patterns of tau-PET distribution, and to compare these patterns to previously published "pathology-driven" ROIs. Tau-PET patterns were identified from a discovery sample comprised of 123 normal controls and patients with mild cognitive impairment or Alzheimer's disease (AD) dementia from the Swedish BioFINDER cohort, who underwent [
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