Evidence map›Paper›PMID 30368765›Full record

ReviewMolecular diagnosis & therapy2018

Advances in Carbon Nanotubes for Malignant Melanoma: A Chance for Treatment.

Elidamar Nunes de Carvalho Lima, José Roberto Castilho Piqueira, Durvanei Augusto Maria

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular diagnosis & therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Nanotechnology as a Promising Method in the Treatment of Skin Cancer.International journal of molecular sciences · 2024
    Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Carbon Nanotubes: Smart Drug/Gene Delivery Carriers.International journal of nanomedicine · 2021
    Review
  11. Article
  12. Toxicity of multi-wall carbon nanotubes inhalation on the brain of rats.Environmental science and pollution research international · 2020
    Article
  13. Article
  14. Toxicity of Carbon Nanotubes as Anti-Tumor Drug Carriers.International journal of nanomedicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Elidamar Nunes de Carvalho LimaTelecommunication and Control Engineering Department, Engineering School, University of São Paulo-USP, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-5906-1076
José Roberto Castilho PiqueiraTelecommunication and Control Engineering Department, Engineering School, University of São Paulo-USP, São Paulo, SP, Brazil. piqueira@lac.usp.br.ORCID http://orcid.org/0000-0003-0153-6686
Durvanei Augusto MariaMolecular Biology Laboratory, Innovation Division, Butantan Institute, 1500, Vital Brasil Avenue, Sao Paulo, 05503-900, Brazil.ORCID http://orcid.org/0000-0003-4120-8468
Universidade de São Paulo · BRInstituto Butantan · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant melanoma is an aggressive skin cancer with limited therapeutic options. Cancer is the second largest cause of death in society and one of the most difficult diseases to treat. Advances in biotechnology have enabled the current use of nanotechnology via the application of nanomaterials, especially as drug delivery systems for the transportation of very small particles. In this context, carbon nanotubes, with a potential role in the diagnosis and treatment of melanoma, are still an emerging research field. Their properties have been extensively studied for the use of antineoplastics drugs, as well as for DNA and RNA interference for the treatment of cancer. However, the most important challenge in nanomedicine is to decrease the toxicity and increase the biocompatibility of the nanomaterials used to transport therapeutic molecules. In this sense, this article addresses the recent advances in the use of carbon nanotubes in melanoma therapy and highlights the opportunities and challenges in this area. The advances and challenges involving these topics are essential to the success of nanoconjugate systems, and studies improving the comprehension of these nanosystems contribute to the development of specific antitumor therapies.

Indexed as

AnimalsHumansMelanomaNanotechnologyNanotubes, CarbonRNA InterferenceNanotubes, Carbon

Identifiers

PMID30368765
OpenAlexW2898172874

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.