Evidence map›Paper›PMID 30368627›Full record

ArticleInternational journal of clinical oncology2019

A Japanese survey of malignant disease in pregnancy.

Yoshiyuki Kobayashi, Tsutomu Tabata, Mayu Omori, Eiji Kondo, Toru Hirata, Kenta Yoshida, Masayuki Sekine, Atsuo Itakura, Takayuki Enomoto, Tomoaki Ikeda

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In one paragraph

Article in International journal of clinical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yoshiyuki KobayashiDepartment of Obstetrics and Gynecology, Mie University School of Medicine, 2-174, Edobashi, Tsu, Mie, 514-8507, Japan.
Tsutomu TabataDepartment of Obstetrics and Gynecology, Mie University School of Medicine, 2-174, Edobashi, Tsu, Mie, 514-8507, Japan. tabatat@clin.medic.mie-u.ac.jp.
Mayu OmoriDepartment of Obstetrics and Gynecology, Mie University School of Medicine, 2-174, Edobashi, Tsu, Mie, 514-8507, Japan.
Eiji KondoDepartment of Obstetrics and Gynecology, Mie University School of Medicine, 2-174, Edobashi, Tsu, Mie, 514-8507, Japan.
Toru HirataDepartment of Obstetrics and Gynecology, Mie University School of Medicine, 2-174, Edobashi, Tsu, Mie, 514-8507, Japan.
Kenta YoshidaDepartment of Obstetrics and Gynecology, Mie University School of Medicine, 2-174, Edobashi, Tsu, Mie, 514-8507, Japan.
Masayuki SekineDepartment of Obstetrics and Gynecology, Niigata University Medical School, 1-757, Asahimachi-street Chuou-ku, Niigata, 951-8510, Japan.
Atsuo ItakuraDepartment of Obstetrics and Gynecology, Juntendo University, 2-1-1, Hongo, Bunkyou-ku, Tokyo, 113-8421, Japan.
Takayuki EnomotoDepartment of Obstetrics and Gynecology, Niigata University Medical School, 1-757, Asahimachi-street Chuou-ku, Niigata, 951-8510, Japan.
Tomoaki IkedaDepartment of Obstetrics and Gynecology, Mie University School of Medicine, 2-174, Edobashi, Tsu, Mie, 514-8507, Japan.
Mie University · JPNiigata University · JPJuntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn recent years, the incidence of malignant disease in pregnancy has been increasing, but there are few large-scale surveys of malignant disease in pregnancy in Japan. The aim of this study was to survey malignant disease occurring during pregnancy in Japan.

methodsMalignant disease in pregnancy was defined as diagnosis or treatment for malignant disease, except in situ carcinoma during pregnancy, or within 1-year postpartum. First, a primary survey questionnaire of the incidence of malignant disease in pregnancy and the number of deliveries over the course of 2014 was sent to 510 medical centers in Japan. Second, the survey questionnaires on the incidence of malignant diseases in pregnancy were collected and analyzed in detail.

resultsOf the 510 medical centers, 411 (81%) responded to the survey. There were 215,372 deliveries and 189 incidents (0.09%) of malignant disease in pregnancy. Of the 189 patients with malignancy, 157 detailed responses about the patients were received. The most frequently encountered cancer types were cervical cancer (36%), breast cancer (24%), and ovarian cancer (15%). During the 2 years after delivery, 15 patients (1 with breast cancer, 2 with ovarian cancer, 3 with hematologic malignancy, 4 with intestinal cancer, and 5 with others) died of the disease; most of them had advanced disease. In particular, 88% of the patients with intestinal cancers at diagnosis had advanced disease, and half of them died of disease.

conclusionsIn Japan, the most common malignancies in pregnancy in order of frequency are cervical cancer, breast cancer, and ovarian cancer. Early diagnosis and appropriate management of cancer during pregnancy are important for improving maternal and neonatal outcomes, because advanced diseases have a poor prognosis.

Indexed as

AdultBreast NeoplasmsFemaleHealth SurveysHumansIncidenceIntestinal NeoplasmsJapanOvarian NeoplasmsPostpartum PeriodPregnancyPregnancy Complications, NeoplasticUterine Cervical NeoplasmsCancerChemotherapyPregnancySurgery

Identifiers

PMID30368627
OpenAlexW2898142859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.