ArticleAIDS and behavior2019
Physical Activity Intensity is Associated with Symptom Distress in the CNICS Cohort.
Article in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 25 citations in OpenAlex.
- Higher steps per day and better diet quality associated with lower symptom burden in adults with HIV: results from the PROSPER-HIV study.Research connections · 2026Article
- Slow and Steady But Not Related to HIV Stigma: Physical Activity in South Africans Living with HIV and Chronic Pain.AIDS and behavior · 2023Article
- Sport and self-esteem in people living with HIV: a cross-sectional study.BMC infectious diseases · 2022Observational
- Patient-Reported Bothersome Symptoms Attributed to Alcohol Use Among People With and Without HIV.AIDS and behavior · 2022Article
- Association between HIV duration and symptom distress among middle-aged and elderly people with HIV-infected in China: a cross-sectional study.BMC geriatrics · 2022Article
- Frailty Syndrome Is Associated with Poorer Self-Reported Sleep Quality Among Older Persons with Human Immunodeficiency Virus.AIDS research and human retroviruses · 2022Article
- Comparison of diet, muscle strength, steps per day and symptoms in people with HIV and HIV-negative peers.Research in nursing & health · 2022Article
- Effects of Two Different Exercise Training Programs Periodization on Anthropometric and Functional Parameters in People Living with HIV: A Randomized Clinical Trial.International journal of exercise science · 2022Article
- A Critical Review of Symptom Management Nursing Science on HIV-Related Fatigue and Sleep Disturbance.International journal of environmental research and public health · 2021Review
- Effects of a symptom management intervention based on group sessions combined with a mobile health application for persons living with HIV in China: A randomized controlled trial.International journal of nursing sciences · 2021Article
- A supervised exercise intervention fails to improve subjective and objective sleep measures among older adults with and without HIV.HIV research & clinical practice · 2020Article
- Associations between symptom severity and treatment burden in people living with HIV.Journal of advanced nursing · 2020Article
- The relationship of cardiorespiratory function, fatigue and depressive symptoms in PLHIV.AIDS care · 2020Article
- An Exploratory Study of Correlates of Allostatic Load in Older People Living With HIV.Journal of acquired immune deficiency syndromes (1999) · 2020Article
- The effect of increased physical activity on symptom burden in older persons living with HIV.AIDS care · 2019Article
- Associations Between Influencing Factors, Perceived Symptom Burden, and Perceived Overall Function Among Adults Living With HIV.The Journal of the Association of Nurses in AIDS Care : JANACArticle
- The PROSPER-HIV Study: A Research Protocol to Examine Relationships Among Physical Activity, Diet Intake, and Symptoms in Adults Living With HIV.The Journal of the Association of Nurses in AIDS Care : JANACObservational
- The Relationship Between Physical Activity and Cardiorespiratory Fitness Among People Living With Human Immunodeficiency Virus Throughout the Life Span.The Journal of cardiovascular nursingArticle
- Symptoms, Lifetime Duration of Estrogen Exposure, and Ovarian Reserve Among Women Living With HIV: A Cross-Sectional Observational Study.The Journal of the Association of Nurses in AIDS Care : JANACObservational
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 1 country.
Funding
Abstract
Symptom distress remains a challenging aspect of living with HIV. Physical activity is a promising symptom management strategy, but its effect on symptom distress has not been examined in a large, longitudinal HIV-infected cohort. We hypothesized that higher physical activity intensity would be associated with reduced symptom distress. We included 5370 people living with HIV (PLHIV) who completed patient-reported assessments of symptom distress, physical activity, alcohol and substance use, and HIV medication adherence between 2005 and 2016. The most frequent and burdensome symptoms were fatigue (reported by 56%), insomnia (50%), pain (46%), sadness (45%), and anxiety (45%), with women experiencing more symptoms and more burdensome symptoms than men. After adjusting for age, sex, race, time, HIV medication adherence, alcohol and substance use, site, and HIV RNA, greater physical activity intensity was associated with lower symptom intensity. Although individual symptoms may be a barrier to physical activity (e.g. pain), the consistent association between symptoms with physical activity suggests that more intense physical activity could mitigate symptoms experienced by PLHIV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.