Evidence map›Paper›PMID 30368596›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2019

Does surgical site infection influence neurological outcome and survival in patients undergoing surgery for metastatic spinal cord compression?

N A Quraishi, M S Ahmed, G Arealis, B M Boszczyk, K L Edwards

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Clinical outcomes of the LORDS strategy for thoracolumbar spinal metastases: a retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

N A QuraishiCentre for Spinal Studies and Surgery, Queens Medical Centre Campus, Nottingham University Hospitals NHS Trust, West Block, D Floor, Derby Road, Nottingham, NG7 2UH, UK. nasquraishi@hotmail.com.ORCID 0000-0002-0444-283X
M S AhmedCentre for Spinal Studies and Surgery, Queens Medical Centre Campus, Nottingham University Hospitals NHS Trust, West Block, D Floor, Derby Road, Nottingham, NG7 2UH, UK.
G ArealisCentre for Spinal Studies and Surgery, Queens Medical Centre Campus, Nottingham University Hospitals NHS Trust, West Block, D Floor, Derby Road, Nottingham, NG7 2UH, UK.
B M BoszczykCentre for Spinal Studies and Surgery, Queens Medical Centre Campus, Nottingham University Hospitals NHS Trust, West Block, D Floor, Derby Road, Nottingham, NG7 2UH, UK.
K L EdwardsCentre for Sports Medicine, Queens Medical Centre, University of Nottingham, Derby Road, Nottingham, NG7 2UH, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMost of the literature on infection after surgery for spinal metastases focuses on incidence and risk factors for surgical site infection (SSI). To the best of our knowledge, there is no report on the influence of infection on neurological outcome and survival in patients undergoing emergent surgery for metastatic spinal cord compression (MSCC).

methodsOur aim was to establish if SSIs adversely affected the neurological outcome and survival in patients with MSCC. We reviewed 318 consecutive patients admitted for surgical intervention for MSCC from October 2005 to October 2012. Morbidity (neurological outcome, length of hospital stay and additional procedures) and survival rates were analysed.

resultsDuring this study period, the incidence of infection was 29/318 (9.1%). The median length of stay in hospital in the infected group was 25 days compared to 13 days in the non-infected group (p = 0.001). Twenty out of the 29 (69%) infected patients underwent an additional procedure (29 procedures in total) compared to 9/289 (3%) non-infected patients (p = 0.001). There was no statistical difference between the two groups with regard to neurological outcome (p = 0.37) but the survival rate was statistically different between the two groups [infected group: median survival 131 days (19-1558) vs. non-infected group: 258 days (5-2696; p = 0.03)].

conclusionSurgical site infection increased the morbidity with considerably longer hospital stay and requirement for additional procedures. Although there was no difference in neurological outcome, the infected group of patients had a significantly shorter survival. These slides can be retrieved under Electronic Supplementary Material.

Indexed as

Nervous System DiseasesSpinal NeoplasmsAgedFemaleHumansIncidenceKaplan-Meier EstimateLength of StayMaleMiddle AgedReoperationRetrospective StudiesRisk FactorsSpinal Cord CompressionSurgical Wound InfectionSurvival RateMetastatic spinal cord compressionSpinal metastasesSurgical site infection

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.