ArticleClinical research in cardiology : official journal of the German Cardiac Society2019
Test-retest reliability of new and conventional echocardiographic parameters of left ventricular systolic function.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 50 citations in OpenAlex.
- Real-time deep learning-based image guiding and automated left ventricular measurements to reduce test-retest variability.Open heart · 2025Trial
- Automated quality indicators for echocardiographic recordings and measurements: consequences for left ventricular global longitudinal strain.European heart journal. Imaging methods and practice · 2026Article
- Cancer Therapy-Related Cardiac Dysfunction: Pooled Incidence of Subclinical and Clinical Presentations Using Multimodal Multi-Parametric Imaging-A Systematic Review and Meta Analysis.Journal of clinical medicine · 2026Review
- Cardiac MRI in cardiac dystrophinopathy: recommendations on imaging.Open heart · 2026Review
- Reproducibility of echocardiographic measurements of left ventricular systolic function: a systematic review and meta-analysis comparing artificial intelligence and clinician estimates.European heart journal. Digital health · 2026Review
- Long-term prognostic impact of one-year change in left ventricular function after a myocardial infarction: insights from the REBUS cohort.European heart journal. Imaging methods and practice · 2026Article
- Left Ventricular Apical Long-Axis Length and Ejection Fraction: A Proof-of-Concept Analysis.Cureus · 2025Article
- Real-time guidance and automated measurements using deep learning to improve echocardiographic assessment of left ventricular size and function.European heart journal. Imaging methods and practice · 2025Article
- Global longitudinal strain in long-term risk prediction after acute coronary syndrome: an investigation of added prognostic value to ejection fraction.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Artificial intelligence-assisted evaluation of cardiac function by oncology staff in chemotherapy patients.European heart journal. Digital health · 2024Article
- Left ventricular ejection fraction: clinical, pathophysiological, and technical limitations.Frontiers in cardiovascular medicine · 2024Review
- Real-time guidance by deep learning of experienced operators to improve the standardization of echocardiographic acquisitions.European heart journal. Imaging methods and practice · 2023Article
- 3D-based strain analysis and cardiotoxicity detection in cancer patients received chemotherapy.BMC cancer · 2023Review
- Heart failure with mildly reduced ejection fraction: from diagnosis to treatment. Gaps and dilemmas in current clinical practice.Heart failure reviews · 2023Review
- Intra-and inter-observer variability of point of care ultrasound measurements to evaluate hemodynamic parameters in healthy volunteers.The ultrasound journal · 2023Article
- Real-time guiding by deep learning during echocardiography to reduce left ventricular foreshortening and measurement variability.European heart journal. Imaging methods and practice · 2023Article
- Correlation of Myocardial Native T1 and Left Ventricular Reverse Remodeling after Valvular Surgery.Journal of clinical medicine · 2023Article
- Reliability of estimating left ventricular ejection fraction in clinical routine: a validation study of the SWEDEHEART registry.Clinical research in cardiology : official journal of the German Cardiac Society · 2023Article
- Low-Volume and High-Intensity Aerobic Interval Training May Attenuate Dysfunctional Ventricular Remodeling after Myocardial Infarction: Data from the INTERFARCT Study.Reviews in cardiovascular medicine · 2023Article
- The Role of Novel Cardiac Imaging for Contemporary Management of Heart Failure.Journal of clinical medicine · 2022Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReliability of left ventricular function measurements depends on actual biological conditions, repeated registrations and their analyses.
objectiveTo investigate test-retest reliability of speckle-tracking-derived strain measurements and its determinants compared to the conventional parameters, such as ejection fraction (EF), LV volumes and mitral annular plane systolic excursion (MAPSE).
methodsIn 30 patients with a wide range of left ventricular function (mean EF 46.4 ± 16.4%, range 14-73%), standard echo views were acquired independently in a blinded fashion by two different echocardiographers in immediate sequence and analyzed off-line by two independent readers, creating 4 data sets per patient. Test-retest reliability of studied parameters was calculated using the smallest detectable change (SDC) and a total, inter-acquisition and inter-reader intra-class correlation coefficient (ICC).
resultsThe smallest detectable change normalized to the mean absolute value of the measured parameter (SDCrel) was lowest for MAPSE (10.7%). SDCrel for EF was similar to GLS (14.2 and 14.7%, respectively), while SDCrel for CS was much higher (35.6%). The intra-class correlation coefficient was excellent (> 0.9) for all measures of the left ventricular function. Intra-patient inter-acquisition reliability (ICCacq) was significantly better than inter-reader reliability (ICCread) (0.984 vs. 0.950, p = 0.03) only for EF, while no significant difference was observed for any other LV function parameter. Mean intra-subject standard deviations were significantly correlated to the mean values for CS and LV volumes, but not for the other studied parameters.
conclusionsIn a test-retest setting, both with normal and impaired left ventricular function, the smallest relative detectable change of EF, GLS and MAPSE was similar (11-15%), but was much higher for CS (35%). Surprisingly, reliability of GLS was not superior to that of EF. Acquisition and reader to a similar extent influenced the reliability of measurements of all left ventricular function measures except for ejection fraction, where the reliability was more dependent on the reader than on the acquisition.
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