ArticleBMJ open2018
Generalised anxiety disorder and hospital admissions: findings from a large, population cohort study.
Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- The prevalence and burden of generalized anxiety disorder in the United States healthcare system: Real-world prevalence and incidence from 2020 to 2023.Journal of mood and anxiety disorders · 2026Article
- The role of the duration of untreated illness (DUI) in generalized anxiety disorder: a cross-sectional, multicenter study.CNS spectrums · 2026Article
- Adult ADHD and comorbid anxiety and depressive disorders: a review of etiology and treatment.Frontiers in psychiatry · 2025Review
- Substance P's Impact on Chronic Pain and Psychiatric Conditions-A Narrative Review.International journal of molecular sciences · 2024Review
- Alcohol Consumption Is a Coping Mechanism for Male Patients with Severe Anxiety Disorders Treated with Antidepressants Monotherapy.Journal of clinical medicine · 2024Article
- A cohort study comparing the effects of medical cannabis for anxiety patients with and without comorbid sleep disturbance.Neuropsychopharmacology reports · 2024Article
- Psychological impact of first admission with cardiovascular disease in a tertiary hospital in Oman.Journal of Taibah University Medical Sciences · 2024Article
- Protecting the Protectors: Moral Injury, Coping Styles, and Mental Health of UK Police Officers and Staff Investigating Child Sexual Abuse Material.Depression and anxiety · 2024Article
- Clinical outcome data of anxiety patients treated with cannabis-based medicinal products in the United Kingdom: a cohort study from the UK Medical Cannabis Registry.Psychopharmacology · 2023Article
- The impact of anxiety on postural control: COPsychophysiology · 2023Article
- Making "Joy Pie" to Stay Joyful: Self-Care Interventions Alleviate College Students' Mental Health Challenges.International journal of environmental research and public health · 2023Article
- Reduced cortical volume of the default mode network in adolescents with generalized anxiety disorder.Depression and anxiety · 2022Article
- Tetrahydrobiopterin and Its Multiple Roles in Neuropsychological Disorders.Neurochemical research · 2022Review
- Effects of Jie Yu Wan on Generalized Anxiety Disorder: A Randomized Clinical Trial.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Generalized Anxiety among Swiss Health Professions and Non-Health Professions Students: An Open Cohort Study over 14 Months in the COVID-19 Pandemic.International journal of environmental research and public health · 2021Article
- Generalised Anxiety Disorder and Depression: Contemporary Treatment Approaches.Advances in therapy · 2021Article
- Reduced neural differentiation of rewards and punishment during passive avoidance learning in adolescents with generalized anxiety disorder.Depression and anxiety · 2021Article
- Reduced top-down attentional control in adolescents with generalized anxiety disorder.Brain and behavior · 2021Article
- Article
- Recent physical conditions and health service utilization in people with common mental disorders and severe mental illness in England: Comparative cross-sectional data from a nationally representative sample.European psychiatry : the journal of the Association of European Psychiatrists · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveGeneralised anxiety disorder (GAD) is the most common anxiety disorder in the general population and has been associated with high economic and human burden. However, it has been neglected in the health services literature. The objective of this study is to assess whether GAD leads to hospital admissions using data from the European Prospective Investigation of Cancer-Norfolk. Other aims include determining whether early-onset or late-onset forms of the disorder, episode chronicity and frequency, and comorbidity with major depressive disorder (MDD) contribute to hospital admissions.
designLarge, population study.
settingUK population-based cohort.
participants30 445 British participants were recruited through general practice registers in England. Of these, 20 919 completed a structured psychosocial questionnaire used to identify presence of GAD. Anxiety was assessed in 1996-2000, and health service use was captured between 1999/2000 and 2009 through record linkage with large, administrative health databases. 17 939 participants had complete data on covariates.
main outcome measurePast-year GAD defined according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition.
resultsIn this study, there were 2.2% (393/17 939) of respondents with GAD. Anxiety was not independently associated with hospital admissions (incidence rate ratio (IRR)=1.04, 95% CI 0.90 to 1.20) over 9 years. However, those whose anxiety was comorbid with depression showed a statistically significantly increased risk for hospital admissions (IRR=1.23, 95% CI 1.02 to 1.49).
conclusionPeople with GAD and MDD comorbidity were at an increased risk for hospital admissions. Clinicians should consider that meeting criteria for a pure or individual disorder at one point in time, such as past-year GAD, does not necessarily predict deleterious health outcomes; rather different forms of the disorder, such as comorbid cases, might be of greater importance.
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