ArticleAIDS research and therapy2018
Non-AIDS defining cancer (NADC) among HIV-infected patients at an oncology tertiary-care center in Mexico.
Article in AIDS research and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- Inflammation and RONS Dysregulation by Redox Enzymes as Mechanistic Links in HIV-1-Cancer Comorbidity.Pathogens (Basel, Switzerland) · 2026Review
- The Trends and Risk Factors of AIDS-Defining Cancers and Non-AIDS-Defining Cancers in Adults Living with and without HIV: A Narrative Review.Journal of cancer epidemiology · 2024Review
- The effect of non-AIDS-defining cancers on people living with HIV.The Lancet. Oncology · 2021Review
- Immunophenotypic characterization of TCR γδ T cells and MAIT cells in HIV-infected individuals developing Hodgkin's lymphoma.Infectious agents and cancer · 2021Article
- Prevalence of osteoporosis and osteopenia in a cohort of HIV positive women with a history of treated neoplasms.SAGE open medicine · 2021Article
- Efavirenz and Lopinavir/Ritonavir Alter Cell Cycle Regulation in Lung Cancer.Frontiers in oncology · 2020Article
- Survival of patients living with HIV and cancer in Cali, Colombia.Colombia medica (Cali, Colombia)Article
- Cancer in people living with HIV-AIDS at a referral hospital in Lima, Peru.Revista peruana de medicina experimental y salud publicaArticle
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNon-AIDS defining cancers (NADCs) have been an increasing cause of morbidity and mortality in patients with HIV. There is no data on the spectrum of NADCs in Mexico. We describe the type of neoplasms, clinical characteristics, and outcomes of HIV-infected patients with NADCs.
methodsWe conducted a retrospective study of all patients with confirmed diagnosis of NADC attending the HIV/AIDS clinic at the National Cancer Institute in Mexico City (a tertiary-care center for adult patients with cancer) from January 1990 to December 2016.
resultsFrom 1126 HIV-positive individuals seen at the institute since 1990, 127 (11.3%) were diagnosed with NADCs; seven patients developed two NADCs during their follow-up. At diagnosis of NADC median age was 43.7 ± 10.9 years; 101 (79.5%) were male; median CD4 was 273 cells/mm
conclusionsHL- and HPV-related neoplasms are the commonest NADC in a cancer referral hospital from a middle-income country with universal access to cART since year 2005. Screening for early anogenital lesions should be emphasized in patients with HIV. It is essential to establish multidisciplinary groups involving Hemato-oncologists, Oncologists, Gynecologists, and HIV Specialists in the treatment of these patients.
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