Evidence map›Paper›PMID 30367636›Full record

ArticleMalaria journal2018

Detection of foci of residual malaria transmission through reactive case detection in Ethiopia.

Endalew Zemene, Cristian Koepfli, Abebaw Tiruneh, Asnakew K Yeshiwondim, Dinberu Seyoum, Ming-Chieh Lee, Guiyun Yan, Delenasaw Yewhalaw

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  11. Epidemiology of malaria in saravan city and its suburbs from 2018 to 2023, Southeast Iran.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024
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  16. High-throughputeLife · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Endalew ZemeneSchool of Medical Laboratory Sciences, Faculty of Health Sciences, Jimma University, Jimma, Ethiopia. endalew2005@yahoo.com.ORCID http://orcid.org/0000-0001-6810-5800
Cristian KoepfliProgram in Public Health, College of Health Sciences, University of California at Irvine, Irvine, CA, 92697, USA.
Abebaw TirunehSchool of Medical Laboratory Sciences, Faculty of Health Sciences, Jimma University, Jimma, Ethiopia.
Asnakew K YeshiwondimPATH/MACEPA, Addis Ababa, Ethiopia.
Dinberu SeyoumDepartment of Statistics, College of Natural Sciences, Jimma University, Jimma, Ethiopia.
Ming-Chieh LeeProgram in Public Health, College of Health Sciences, University of California at Irvine, Irvine, CA, 92697, USA.
Guiyun YanProgram in Public Health, College of Health Sciences, University of California at Irvine, Irvine, CA, 92697, USA.
Delenasaw YewhalawSchool of Medical Laboratory Sciences, Faculty of Health Sciences, Jimma University, Jimma, Ethiopia.
Jimma University · ETUniversity of California, Irvine · US

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
Vector Biology of Invasive Anopheles stephensi in Rural to Urban Landscapes in EthiopiaU19AI129326 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI Delenasaw Yewhalaw · 2017 to 2026
$19.9M
Ecology of African Highland MalariaR01AI050243 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI YAN, GUIYUN · 2001 to 2018
$8.8M
Research Training in Mosquito Genomics and Bioinformat*D43TW001505 · FIC · UNIVERSITY OF CALIFORNIA-IRVINE · PI Guiyun Yan · 2000 to 2026
$6.0M
FIC NIH HHS D43 TW001505NCATS NIH HHS UL1 TR001414NIAID NIH HHS R01 AI050243NIAID NIH HHS U19 AI129326
6 · The paper itself

Abstract

backgroundSub-microscopic and asymptomatic infections could be bottlenecks to malaria elimination efforts in Ethiopia. This study determined the prevalence of malaria, and individual and household-level factors associated with Plasmodium infections obtained following detection of index cases in health facilities in Jimma Zone.

methodsIndex malaria cases were passively detected and tracked in health facilities from June to November 2016. Moreover, family members of the index houses and neighbours located within approximately 200 m from the index houses were also screened for malaria.

resultsA total of 39 index cases initiated the reactive case detection of 726 individuals in 116 households. Overall, the prevalence of malaria using microscopy and PCR was 4.0% and 8.96%, respectively. Seventeen (43.6%) of the index cases were from Doyo Yaya kebele, where parasite prevalence was higher. The majority of the malaria cases (90.74%) were asymptomatic. Fever (AOR = 12.68, 95% CI 3.34-48.18) and history of malaria in the preceding 1 year (AOR = 3.62, 95% CI 1.77-7.38) were significant individual-level factors associated with detection of Plasmodium infection. Moreover, living in index house (AOR = 2.22, 95% CI 1.16-4.27), house with eave (AOR = 2.28, 95% CI 1.14-4.55), area of residence (AOR = 6.81, 95% CI 2.49-18.63) and family size (AOR = 3.35, 95% CI 1.53-7.33) were main household-level predictors for residual malaria transmission.

conclusionThe number of index cases per kebele may enhance RACD efforts to detect additional malaria cases in low transmission settings. Asymptomatic and sub-microscopic infections were high in the study area, which need new or improved surveillance tools for malaria elimination efforts.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolEthiopiaFemaleHumansInfantMalariaMaleMicroscopyMiddle AgedPlasmodiumPolymerase Chain ReactionEthiopiaLow-transmission settingMalariaReactive case detectionResidual malaria transmission

Identifiers

PMID30367636
PMCPMC6203988
OpenAlexW2898189947

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.