Evidence map›Paper›PMID 30367635›Full record

ArticleBMC medical genomics2018

Current landscape of personalized medicine adoption and implementation in Southeast Asia.

Huey Yi Chong, Pascale A Allotey, Nathorn Chaiyakunapruk

Registry-linked trialAbstract read
In one paragraph

Article in BMC medical genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05562440 (The Perspective of Healthy Individuals on Breast Cancer Risk Prediction Report in The Indonesian Population), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05562440 nacompletednot on this mapstarted 2022, after this paper: background citation

The Perspective of Healthy Individuals on Breast Cancer Risk Prediction Report in The Indonesian Population (Perspektif Para Individu Sehat Terhadap Laporan Prediksi Risiko Kanker Payudara)

TypeinterventionalSponsorNalagenetics Pte LtdRan2022 to 2023Enrolled10ConditionsBreast CancerArmsFocus Group Discussion
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Frontiers in pharmacology · 2025
    Pooled it
  2. Pooled it
  3. Review
  4. Exploring Current Procedural Terminology Codes for Physical Therapist Evaluations in the United States: Results of a Feasibility Study.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Article
  5. Case Report: Clinical implications ofFrontiers in pediatrics · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
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  18. Review
  19. Fighting Cancer around the World: A Framework for Action.Healthcare (Basel, Switzerland) · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Huey Yi ChongSchool of Pharmacy, Monash University Malaysia, Subang Jaya, Selangor, Malaysia.
Pascale A AlloteyUnited Nations University International Institute for Global Health, Kuala Lumpur, Malaysia.
Nathorn ChaiyakunaprukSchool of Pharmacy, Monash University Malaysia, Subang Jaya, Selangor, Malaysia. nathorn.chaiyakunapruk@monash.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe emergence of personalized medicine (PM) has raised some tensions in healthcare systems. PM is expensive and health budgets are constrained - efficient healthcare delivery is therefore critical. Notwithstanding the cost, many countries have started to adopt this novel technology, including resource-limited Southeast Asia (SEA) countries. This study aimed to describe the status of PM adoption in SEA, highlight the challenges and to propose strategies for future development.

methodsThe study included scoping review and key stakeholder interviews in four focus countries - Indonesia, Malaysia, Singapore, and Thailand. The current landscape of PM adoption was evaluated based on an assessment framework of six key themes - healthcare system, governance, access, awareness, implementation, and data. Six PM programs were evaluated for their financing and implementation mechanisms.

resultsThe findings revealed SEA has progressed in adopting PM especially Singapore and Thailand. A regional pharmacogenomics research network has been established. However, PM policies and programs vary significantly. As most PM programs are champion-driven and the available funding is limited, the current PM distribution has the potential to widen existing health disparities. Low PM awareness in the society and the absence of political support with financial investment are fundamental barriers. There is a clear need to broaden opportunities for critical discourse about PM especially for policymakers. Multi-stakeholder, multi-country strategies need to be prioritized in order to leverage resources and expertise.

conclusionsAdopting PM remains in its infancy in SEA. To achieve an effective PM adoption, it is imperative to balance equity issues across diverse populations while improving efficiency in healthcare.

Indexed as

Precision MedicineAwarenessDatabases, FactualDelivery of Health CareFemaleHealthcare DisparitiesHumansIndonesiaInterviews as TopicMalaysiaMaleSingaporeThailandImplementationPersonalized medicinePharmacogenomicsSoutheast Asia

Identifiers

PMID30367635
PMCPMC6203971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.