ArticleBMC public health2018
The association between fetal-stage exposure to the China famine and risk of diabetes mellitus in adulthood: results from the China health and retirement longitudinal study.
Article in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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20 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Early-Life Exposure to the Chinese Famine of 1959-1961 and Type 2 Diabetes in Adulthood: A Systematic Review and Meta-Analysis.Nutrients · 2022Pooled it
- Severe maternal undernutrition during pregnancy and its long-term effects on the offspring health, with a focus on kidney health.Pediatric nephrology (Berlin, Germany) · 2025Review
- Unveiling the long-term impact: exploring the link between exposure to the great Chinese famine and health-related quality of life in middle-aged and elderly populations through propensity score matching.BMC public health · 2025Article
- The relationship between childhood hunger experiences and activities of daily living disability: a mediating role of depression.BMC public health · 2024Article
- Famine mortality and contributions to later-life type 2 diabetes at the population level: a synthesis of findings from Ukrainian, Dutch and Chinese famines.BMJ global health · 2024Review
- Analysis of study Global Burden of Disease in 2021: global, regional, and national burden of nutritional deficiency from 1990 to 2021.Frontiers in nutrition · 2024Article
- Separate and combined effects of famine exposure and menarche age on metabolic syndrome among the elderly: a cross-sectional study in China.BMC women's health · 2023Article
- Famine exposure in early life and type 2 diabetes in adulthood: findings from prospective studies in China.Nutrition research and practice · 2023Article
- Upper arm length and knee height are associated with diabetes in the middle-aged and elderly: evidence from the China Health and Retirement Longitudinal Study.Public health nutrition · 2023Article
- Combined effects of air pollution in adulthood and famine exposure in early life on type 2 diabetes.Environmental science and pollution research international · 2022Article
- Adolescence exposure to China's great famine period and the association of metabolic syndrome in adulthood: a retrospective study.BMC public health · 2022Article
- Association of famine exposure and the serum calcium level in healthy Chinese adults.Frontiers in endocrinology · 2022Article
- Article
- The relationship between famine exposure during early life and carotid plaque in adulthood.European journal of clinical nutrition · 2021Article
- Combined Effect of Famine Exposure and Obesity Parameters on Hypertension in the Midaged and Older Adult: A Population-Based Cross-Sectional Study.BioMed research international · 2021Article
- Article
- Ten SNPs May Affect Type 2 Diabetes Risk in Interaction with Prenatal Exposure to Chinese Famine.Nutrients · 2020Article
- Early-life exposure to the Chinese Famine and subsequent T2DM.Nature reviews. Endocrinology · 2020Article
- Reply to 'Early-life exposure to the Chinese Famine and subsequent T2DM'.Nature reviews. Endocrinology · 2020Article
- Early-life exposure to the Chinese famine of 1959-61 and risk of Hyperuricemia: results from the China health and retirement longitudinal study.BMC public health · 2020Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundThe associations of famine exposure with diabetes risk in adulthood are still unclear. This study aimed to explore the association between famine exposure in early life and risk of diabetes in adulthood.
methodsA total of 4138 subjects were selected from the data of the China Health and Retirement Longitudinal Study (CHARLS) 2011-2012. Diabetes was diagnosed as fasting plasma glucose (FPG) ≥7.0 mmol/L, glycated haemoglobin (HbA
resultsThe prevalence of diabetes in the non-exposed, fetal-stage exposed, infant-stage exposed, and preschool-stage exposed groups were 9.0, 13.6, 12.7 and 10.8%, respectively. Compared with the age-balanced control group, the fetal-stage exposed group was associated with the elevated risk of diabetes in later life after adjusting for covariates (OR = 1.37; 95%CI: 1.09-1.72; P = 0.008). Stratified analysis showed that the association between prenatal famine exposure and diabetes risk in adulthood was comparable between severely affected areas and less severely affected areas (P for interaction =0.153).
conclusionsFamine exposure in fetal stages was associated with the elevated diabetes risk in adults, which could be the critical periods for relative intervention.
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