ArticleBMC plant biology2018
Wheat Bax Inhibitor-1 interacts with TaFKBP62 and mediates response to heat stress.
Article in BMC plant biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Technological advances in imaging and modelling of leaf structural traits: a review of heat stress in wheat.Journal of experimental botany · 2026Review
- The VaATG6-VaBI-1 module coordinates ER-associated autophagy and ROS homeostasis for cold tolerance in grapevine.Molecular horticulture · 2026Article
- Transcriptomic Meta-Analysis Reveals Hub Genes Integrating Multiple Abiotic Stress Responses in Wheat.Food science & nutrition · 2025Article
- Characterization of theInternational journal of molecular sciences · 2024Article
- Article
- Duplicate Genes Contribute to Variability in Abiotic Stress Resistance in Allopolyploid Wheat.Plants (Basel, Switzerland) · 2023Review
- Physiological and gene expression responses involved in teak (Tectona grandis L.) seedlings exposed to osmotic and salt stressors.Molecular biology reports · 2023Article
- Fine mapping of a QTL and identification of candidate genes associated with cold tolerance during germination in peanut (Frontiers in plant science · 2023Article
- Assessing the Heat Tolerance of Meiosis in Spanish Landraces of Tetraploid WheatPlants (Basel, Switzerland) · 2022Article
- Overcoming Reproductive Compromise Under Heat Stress in Wheat: Physiological and Genetic Regulation, and Breeding Strategy.Frontiers in plant science · 2022Review
- Characteristics ofInternational journal of molecular sciences · 2021Article
- Differential responses of anthers of stress tolerant and sensitive wheat cultivars to high temperature stress.Planta · 2021Article
- Transcription Analysis of the Stress and Immune Response Genes to Temperature Stress inFrontiers in physiology · 2019Article
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundHeat stress is a severe environmental stress that affects plant growth and reduces yield. Bax inhibitor-1 (BI-1) is a cytoprotective protein that is involved in the response to biotic and abiotic stresses. The Arabidopsis (Arabidopsis thaliana) BI-1 mutants atbi1-1 and atbi1-2 are hypersensitive to heat stress, and AtBI-1 overexpression rescues thermotolerance deficiency in atbi1 plants. Nevertheless, the mechanism of BI-1 in plant thermotolerance is still unclear.
resultsWe identified a wheat (Triticum aestivum L.) BI-1 gene, TaBI-1.1, which was highly upregulated in an RNA sequencing (RNA-seq) analysis of heat-treated wheat. The upregulation of TaBI-1.1 under heat stress was further demonstrated by real time quantitative PCR (qRT-PCR) and β-glucuronidase (GUS) staining. Compared with the wild type Col-0, the atbi1-2 mutant is hypersensitive to heat stress, and constitutive expression of TaBI-1.1 in atbi1-2 (35S::TaBI-1.1/ atbi1-2) rescued the deficiency of atbi1-2 under heat stress. Furthermore, we identified TaFKBP62 as a TaBI-1.1-interacting protein that co-localized with TaBI-1.1 on the endoplasmic reticulum (ER) membrane and enhanced heat stress tolerance. Additionally, HSFA2, HSFB1, ROF1, HSP17.4B, HSP17.6A, HSP17.8, HSP70B, and HSP90.1 expression levels were suppressed in atbi1-2 plants under heat stress. In contrast, 35S::TaBI-1.1/atbi1-2 relieved the inhibitory effect of AtBI-1 loss of function.
conclusionsTaBI-1.1 interacted with TaFKBP62 and co-localized with TaFKBP62 on the ER membrane. Both TaBI-1.1 and AtBI-1 regulated the expression of heat-responsive genes and were conserved in plant thermotolerance.
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