Evidence map›Paper›PMID 30367570›Full record

ArticleBMC bioinformatics2018

Efficient computation of motif discovery on Intel Many Integrated Core (MIC) Architecture.

Shaoliang Peng, Minxia Cheng, Kaiwen Huang, YingBo Cui, Zhiqiang Zhang, Runxin Guo, Xiaoyu Zhang, Shunyun Yang, Xiangke Liao, Yutong Lu and 2 more

Abstract read
In one paragraph

Article in BMC bioinformatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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  3. Frontiers in genetics · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shaoliang PengCollege of Computer Science and Electronic Engineering & National Supercomputing Centre in Changsha, Hunan University, Changsha, 410082, China. pengshaoliang@nudt.edu.cn.
Minxia ChengCollege of Computer Science and Electronic Engineering & National Supercomputing Centre in Changsha, Hunan University, Changsha, 410082, China.
Kaiwen HuangSchool of Computer Science, National University of Defense Technology, Changsha, 410073, China.
YingBo CuiSchool of Computer Science, National University of Defense Technology, Changsha, 410073, China.
Zhiqiang ZhangSchool of Computer Science, National University of Defense Technology, Changsha, 410073, China.
Runxin GuoSchool of Computer Science, National University of Defense Technology, Changsha, 410073, China.
Xiaoyu ZhangSchool of Computer Science, National University of Defense Technology, Changsha, 410073, China.
Shunyun YangSchool of Computer Science, National University of Defense Technology, Changsha, 410073, China.
Xiangke LiaoSchool of Computer Science, National University of Defense Technology, Changsha, 410073, China.
Yutong LuNational Supercomputer Center in Guangzhou, Guangzhou, 510275, China.
Quan ZouSchool of Computer Science and Technology, Tianjin University, Tianjin, 300350, China. zouquan@nclab.net.
Benyun ShiSchool of Cyberspace, Hangzhou Dianzi University, Hangzhou, 310018, China. benyunshi@outlook.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNovel sequence motifs detection is becoming increasingly essential in computational biology. However, the high computational cost greatly constrains the efficiency of most motif discovery algorithms.

resultsIn this paper, we accelerate MEME algorithm targeted on Intel Many Integrated Core (MIC) Architecture and present a parallel implementation of MEME called MIC-MEME base on hybrid CPU/MIC computing framework. Our method focuses on parallelizing the starting point searching method and improving iteration updating strategy of the algorithm. MIC-MEME has achieved significant speedups of 26.6 for ZOOPS model and 30.2 for OOPS model on average for the overall runtime when benchmarked on the experimental platform with two Xeon Phi 3120 coprocessors.

conclusionsFurthermore, MIC-MEME has been compared with state-of-arts methods and it shows good scalability with respect to dataset size and the number of MICs. Source code: https://github.com/hkwkevin28/MIC-MEME .

Indexed as

Nucleotide MotifsPromoter Regions, GeneticRegulatory Elements, TranscriptionalSoftwareAlgorithmsComputational BiologyComputer GraphicsDatabases, GeneticHumansInternetTranscription FactorsTranscription FactorsMEMEMICMotif discoveryOffload mode

Identifiers

PMID30367570
PMCPMC6101076

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.