Evidence map›Paper›PMID 30367336›Full record

ReviewNeuroscience bulletin2019

Pericyte Plasticity in the Brain.

Gabryella S P Santos, Luiz A V Magno, Marco A Romano-Silva, Akiva Mintz, Alexander Birbrair

Abstract readReview
In one paragraph

Review in Neuroscience bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Glioma Pericytes Promote Angiogenesis by Producing Periostin.Cellular and molecular neurobiology · 2022
    Review
  11. Review
  12. Article
  13. Review
  14. Circulating Nestin-GFPStem cell reviews and reports · 2021
    Article
  15. Hematopoietic stem cell stretches and moves in its bone marrow niche.Critical reviews in oncology/hematology · 2021
    Review
  16. Article
  17. Pericyte morphology and function.Histology and histopathology · 2021
    Review
  18. Sensory nerves in the spotlight of the stem cell niche.Stem cells translational medicine · 2021
    Review
  19. Article
  20. Clearance Systems in the Brain, From Structure to Function.Frontiers in cellular neuroscience · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabryella S P SantosDepartamento de Patologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil.
Luiz A V MagnoDepartment of Mental Health, Federal University of Minas Gerais, Belo Horizonte, MG, 30130-100, Brazil.
Marco A Romano-SilvaDepartment of Mental Health, Federal University of Minas Gerais, Belo Horizonte, MG, 30130-100, Brazil.
Akiva MintzDepartment of Radiology, Columbia University Medical Center, New York, NY, 10032, USA.
Alexander BirbrairDepartamento de Patologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil. birbrair@icb.ufmg.br.

Funding

Sub-component for Institution # 16-01848 Novel moleculary targeted therapy of GBMP01CA207206 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DEBINSKI, WALDEMAR · 2017 to 2021
$9.0M
Therapeutically Exploiting a Newly Isolated Neural-Like Stem Cell Against GSBR01CA179072 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MINTZ, AKIVA · 2015 to 2020
$1.6M
NCI NIH HHS P01 CA207206NCI NIH HHS R01 CA179072
6 · The paper itself

Abstract

Cerebral pericytes are perivascular cells that stabilize blood vessels. Little is known about the plasticity of pericytes in the adult brain in vivo. Recently, using state-of-the-art technologies, including two-photon microscopy in combination with sophisticated Cre/loxP in vivo tracing techniques, a novel role of pericytes was revealed in vascular remodeling in the adult brain. Strikingly, after pericyte ablation, neighboring pericytes expand their processes and prevent vascular dilatation. This new knowledge provides insights into pericyte plasticity in the adult brain.

Indexed as

Vascular RemodelingAnimalsBrainBrain DiseasesCapillariesCellular MicroenvironmentDiabetic RetinopathyEndothelial CellsHumansPericytesBlood vesselBrainPericytesPlasticity

Identifiers

PMID30367336
PMCPMC6527663

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.