ArticleJournal of perinatology : official journal of the California Perinatal Association2019
Early inspired oxygen and intermittent hypoxemic events in extremely premature infants are associated with asthma medication use at 2 years of age.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk of asthma in preterm infants with bronchopulmonary dysplasia: a systematic review and meta-analysis.World journal of pediatrics : WJP · 2023Pooled it
- Hypoxemia Surrounding Enteral Feeds in Preterm Infants Receiving Extended Continuous Positive Airway Pressure.Research square · 2026Article
- The impact of neonatal respiratory distress syndrome on subsequent preschool wheezing in very preterm infants: a multicenter cohort study.Clinics (Sao Paulo, Brazil) · 2026Article
- Hydrogen sulfide alleviates hyperoxia effects on mitochondria in human developing airway smooth muscle.JCI insight · 2026Article
- Association between intermittent hypoxemia and COVID-19 related isolation and pulmonary outcomes through 2 years of age in infants born preterm.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Hyperoxia-induced senescence in fetal airway smooth muscle cells: role of mitochondrial reactive oxygen species and endoplasmic reticulum stress.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Effect of Intermittent Hypoxemia and Hyperoxemia during the Neonatal Period on Control of Breathing Function among Infants Born Extremely Preterm.The Journal of pediatrics · 2025Observational
- Risk factors for and outcomes of intraoperative desaturation in neonates undergoing non-cardiac surgery: a retrospective study.World journal of pediatric surgery · 2025Article
- Apnea of Prematurity and Oxidative Stress: Potential Implications.Antioxidants (Basel, Switzerland) · 2024Review
- BMAL1 sex-specific effects in the neonatal mouse airway exposed to moderate hyperoxia.Physiological reports · 2024Article
- Maturation of cardioventilatory physiological trajectories in extremely preterm infants.Pediatric research · 2024Article
- Association between Intermittent Hypoxemia and NICU Length of Stay in Preterm Infants.Neonatology · 2024Article
- Exogenous hydrogen sulfide attenuates hyperoxia effects on neonatal mouse airways.American journal of physiology. Lung cellular and molecular physiology · 2024Article
- Hypoxemia events in preterm neonates are associated with urine oxidative biomarkers.Pediatric research · 2023Article
- Prematurity-associated wheeze: current knowledge and opportunities for further investigation.Pediatric research · 2023Review
- Effects of early postnatal hyperoxia exposure combined with early ovalbumin sensitization on lung inflammation and bacterial flora in a juvenile mouse model of asthma.Frontiers in microbiology · 2023Article
- Pulse oximetry reliability for detection of hypoxemia under motion in extremely premature infants.Pediatric research · 2023Article
- Oxygen and mechanical stretch in the developing lung: risk factors for neonatal and pediatric lung disease.Frontiers in medicine · 2023Review
- Neonatal intermittent hypoxia persistently impairs lung vascular development and induces long-term lung mitochondrial DNA damage.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- The Association between Asthma and OSA in Children.Children (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveExtremely premature infants are at risk for childhood wheezing. Early respiratory support and intermittent hypoxemia (IH) events may be associated with adverse breathing outcomes. STUDY
designA single-center retrospective cohort study of 137 premature infants <28 weeks gestational age characterized the associations of cumulative oxygen, cumulative mean airway pressure, IH, and oxygen saturation (SpO
resultsReported asthma medication use was 46%. At 1-3 days of age, elevated cumulative oxygen exposure, increased daily IH, and lower mean SpO
conclusionIncreased oxygen and frequent IH events during just the first 3 days of age may help identify extremely premature newborns at risk for symptomatic childhood wheezing requiring prescription asthma medications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.