Evidence map›Paper›PMID 30367098›Full record

ArticleScientific reports2018

Protein-Engineered Large Area Adipose-derived Stem Cell Sheets for Wound Healing.

Jongbeom Na, Seung Yong Song, Jae Dong Kim, Minsu Han, June Seok Heo, Chae Eun Yang, Hyun Ok Kim, Dae Hyun Lew, Eunkyoung Kim

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Current status and future prospects of stomatology research.Journal of Zhejiang University. Science. B · 2023
    Article
  4. Review
  5. Review
  6. Review
  7. Effect of composite biodegradable biomaterials on wound healing in diabetes.Frontiers in bioengineering and biotechnology · 2022
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jongbeom NaDepartment of Chemical and Biomolecular Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
Seung Yong SongInstitute for Human Tissue Restoration, Department of Plastic & Reconstructive Surgery, Yonsei University College of Medicine, Seoul, South Korea.
Jae Dong KimDepartment of Chemical and Biomolecular Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
Minsu HanDepartment of Chemical and Biomolecular Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
June Seok HeoCell Therapy Center, Severance Hospital, Yonsei University College of Medicine, Department of Laboratory Medicine, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
Chae Eun YangInstitute for Human Tissue Restoration, Department of Plastic & Reconstructive Surgery, Yonsei University College of Medicine, Seoul, South Korea.ORCID http://orcid.org/0000-0001-8128-791X
Hyun Ok KimCell Therapy Center, Severance Hospital, Yonsei University College of Medicine, Department of Laboratory Medicine, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.
Dae Hyun LewInstitute for Human Tissue Restoration, Department of Plastic & Reconstructive Surgery, Yonsei University College of Medicine, Seoul, South Korea. DHLEW@yuhs.ac.
Eunkyoung KimDepartment of Chemical and Biomolecular Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea. eunkim@yonsei.ac.kr.

Funding

Korea Health Industry Development Institute (KHIDI) HI15C0942National Research Foundation of Korea (NRF) 2016K1A1A2912753
6 · The paper itself

Abstract

Human adipose-derived stem cells (hADSCs) formed robust cell sheets by engineering the cells with soluble cell adhesive molecules (CAMs), which enabled unique approaches to harvest large area hADSC sheets. As a soluble CAM, fibronectin (FN) (100 pg/ml) enhanced the cell proliferation rate and control both cell-to-cell and cell-to-substrate interactions. Through this engineering of FN, a transferrable hADSC sheet was obtained as a free-stranding sheet (122.6 mm

Indexed as

Protein EngineeringWound HealingAdipose TissueAnimalsBridged Bicyclo Compounds, HeterocyclicFibronectinsHumansInfrared RaysMesenchymal Stem CellsMesenchymal Stem Cell TransplantationMicePolymersSkin DiseasesBridged Bicyclo Compounds, HeterocyclicFibronectinspoly(3,4-ethylene dioxythiophene)Polymers

Identifiers

PMID30367098
PMCPMC6203842

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.