ArticleNature communications2018
Multifunctional sequence-defined macromolecules for chemical data storage.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed.
- Sequence-Controlled Copolymers Through Selective Ring-Opening Polymerization of Multiunit Macrolactones.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Highly robust molecular information carriers for traceability of plastic materials.Nature communications · 2026Article
- Circularity in Sequence-Controlled Copolyamides Enabled by Regioselective Enzymatic Hydrolysis.Journal of the American Chemical Society · 2026Article
- Photoresponsive DNA steganography for secure information transmission by nanopore.National science review · 2026Article
- Article
- Efficient Solution-Phase Synthesis of Sequence-Defined Oligourethanes with Precise Chirality Control.Macromolecular rapid communications · 2025Article
- On-Resin Recycling of Acid-Labile Linker Enables the Reuse of Solid Support for Fmoc-Based Solid Phase Synthesis.Macromolecular rapid communications · 2025Article
- Towards next-generation DNA encryption via an expanded genetic system.National science review · 2025Article
- Article
- Complex Sequence-Defined Heteropolymers Enable Controlled Film Growth in Layer-By-Layer Assembly.Macromolecular rapid communications · 2024Article
- Template-based copying in chemically fuelled dynamic combinatorial libraries.Nature chemistry · 2024Article
- Revealing the Effect of Stereocontrol on Intermolecular Interactions between Abiotic, Sequence-Defined Polyurethanes and a Ligand.ACS biomaterials science & engineering · 2024Article
- Chemical and linguistic considerations for encoding Chinese characters: an embodiment using chain-end degradable sequence-defined oligourethanes created by consecutive solid phase click chemistry.Chemical science · 2024Article
- Design of Microstructure-Engineered Polymers for Energy and Environmental Conservation.JACS Au · 2023Review
- Enthalpy and entropy synergistic regulation-based programmable DNA motifs for biosensing and information encryption.Science advances · 2023Article
- Review
- Nondestructive Sequencing of Enantiopure Oligoesters by Nuclear Magnetic Resonance Spectroscopy.JACS Au · 2022Article
- Molecular Encryption and Steganography Using Mixtures of Simultaneously Sequenced, Sequence-Defined Oligourethanes.ACS central science · 2022Article
- Molecular data storage with zero synthetic effort and simple read-out.Scientific reports · 2022Article
- Semiautomated synthesis of sequence-defined polymers for information storage.Science advances · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Sequence-defined macromolecules consist of a defined chain length (single mass), end-groups, composition and topology and prove promising in application fields such as anti-counterfeiting, biological mimicking and data storage. Here we show the potential use of multifunctional sequence-defined macromolecules as a storage medium. As a proof-of-principle, we describe how short text fragments (human-readable data) and QR codes (machine-readable data) are encoded as a collection of oligomers and how the original data can be reconstructed. The amide-urethane containing oligomers are generated using an automated protecting-group free, two-step iterative protocol based on thiolactone chemistry. Tandem mass spectrometry techniques have been explored to provide detailed analysis of the oligomer sequences. We have developed the generic software tools Chemcoder for encoding/decoding binary data as a collection of multifunctional macromolecules and Chemreader for reconstructing oligomer sequences from mass spectra to automate the process of chemical writing and reading.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.