Evidence map›Paper›PMID 30366938›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2019

A Multicenter Phase II Study of AMG 337 in Patients with

Eric Van Cutsem, Boguslawa Karaszewska, Yoon-Koo Kang, Hyun Cheol Chung, Veena Shankaran, Salvatore Siena, Ning F Go, Hui Yang, Marco Schupp, David Cunningham

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Bioactive Products Targeting C-Met As Potential Antitumour Drugs.Anti-cancer agents in medicinal chemistry · 2025
    Review
  13. Gastric cancer patient withAME case reports · 2025
    Article
  14. Review
  15. MET Oncogene Targeting for Cancer Immunotherapy.International journal of molecular sciences · 2024
    Review
  16. Article
  17. Article
  18. TargetingCancers · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 7 countries.

Eric Van CutsemDepartment of Digestive Oncology, University Hospitals Gasthuisberg, Leuven, and KU Leuven, Leuven, Belgium. eric.vancutsem@uzleuven.be.
Boguslawa KaraszewskaDepartment of Oncology, Przychodnia Lekarska NZOZ KOMED, Konin, Poland.
Yoon-Koo KangDepartment of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Hyun Cheol ChungDepartment of Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, South Korea.
Veena ShankaranDivision of Medical Oncology, University of Washington, Seattle, Washington.
Salvatore SienaDepartment of Hematology and Oncology, Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda and Dipartimento di Oncologia and Emato-Oncologia, Università degli Studi di Milano, Milan, Italy.ORCID https://orcid.org/0000-0002-2681-2846
Ning F GoClinical Biomarkers and Diagnostics, Amgen Inc., Thousand Oaks, California.
Hui YangGlobal Biostatistical Sciences, Amgen Inc., Thousand Oaks, California.ORCID https://orcid.org/0000-0002-5088-046X
Marco SchuppGlobal Development, Amgen (Europe) GmbH, Zug, Switzerland.
David CunninghamDepartment of Medicine, Royal Marsden Hospital, London, United Kingdom.
Amgen (United States) · USAmgen (Switzerland) · CHAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITRoyal Marsden Hospital · GBState University of Applied Sciences in Konin · PLUniversitair Ziekenhuis Leuven · BEUniversity of Ulsan · KRUniversity of Washington Medical Center · USYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose

resultsOf 2101 patients screened for

conclusionsAMG 337 showed antitumor activity in

Indexed as

AdenocarcinomaCarcinoma, Non-Small-Cell LungLung NeoplasmsStomach NeoplasmsAdultAntineoplastic Combined Chemotherapy ProtocolsDisease-Free SurvivalEsophagogastric JunctionFluorouracilHumansPyridonesTriazolesAMG 337FluorouracilPyridonesTriazoles

Identifiers

PMID30366938
OpenAlexW2898197409

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.