Evidence map›Paper›PMID 30366921›Full record

Trial reportBlood2018

Bortezomib overcomes the negative impact of CXCR4 mutations on survival of Waldenstrom macroglobulinemia patients.

Romanos Sklavenitis-Pistofidis, Marzia Capelletti, Chia-Jen Liu, Mairead Reidy, Oksana Zavidij, Daisy Huynh, Patrick Henrick, Alexandra Savell, Kaitlen Reyes, Bradley Rivotto and 6 more

Abstract readClinical TrialLetter
In one paragraph

Trial report in Blood, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. How to Sequence Therapies in Waldenström Macroglobulinemia.Current treatment options in oncology · 2021
    Review
  10. Review
  11. Review
  12. Genomic Landscape of Waldenström Macroglobulinemia and Its Impact on Treatment Strategies.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2020
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Romanos Sklavenitis-PistofidisDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.
Marzia CapellettiDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.
Chia-Jen LiuDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.
Mairead ReidyDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.
Oksana ZavidijDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.
Daisy HuynhDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.
Patrick HenrickDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.
Alexandra SavellDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.
Kaitlen ReyesDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.
Bradley RivottoDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.
Mark BustorosDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.
Adriana Perilla-GlenDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.
Lorenzo TrippaDepartment of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA.
Jorge J CastilloDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.
Steven P TreonDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.
Irene M GhobrialDepartment of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and.

Funding

(PQ1) Genomic characterization of mesenchymal stromal cells in Monoclonal Gammopathy of Undermined Significance (MGUS)R01CA205954 · NCI · DANA-FARBER CANCER INST · PI GHOBRIAL, IRENE M. · 2016 to 2020
$2.6M
NCI NIH HHS R01 CA205954
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationWaldenstrom MacroglobulinemiaBortezomibFemaleFollow-Up StudiesHumansMaleReceptors, CXCR4BortezomibCXCR4 protein, humanReceptors, CXCR4

Identifiers

PMID30366921
PMCPMC6293872

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.