Evidence map›Paper›PMID 30366904›Full record

ArticleGenes & development2018

Mutations in

Claudio Cantù, Anastasia Felker, Dario Zimmerli, Karin D Prummel, Elena M Cabello, Elena Chiavacci, Kevin M Méndez-Acevedo, Lucia Kirchgeorg, Sibylle Burger, Jorge Ripoll and 8 more

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 50 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Genome Editing and Myocardial Development.Advances in experimental medicine and biology · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Intestinal Wnt in the transition from physiology to oncology.World journal of clinical oncology · 2022
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 3 countries.

Claudio Cantù *Institute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.
Anastasia Felker *Institute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.
Dario Zimmerli *Institute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.
Karin D PrummelInstitute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.
Elena M CabelloInstitute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.
Elena ChiavacciInstitute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.
Kevin M Méndez-AcevedoElectrochemical Signaling in Development and Disease, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin-Buch, Germany.
Lucia KirchgeorgInstitute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.
Sibylle BurgerInstitute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.
Jorge RipollDepartment of Bioengineering and Aerospace Engineering, Universidad Carlos III de Madrid, 28911 Madrid, Spain.
Tomas ValentaInstitute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.
George HausmannInstitute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.
Nathalie VilainSwiss Institute for Experimental Cancer Research (ISREC), École Polytechnique Fédérale de Lausanne (EPFL), School of Life Sciences, 1015 Lausanne, Switzerland.
Michel AguetSwiss Institute for Experimental Cancer Research (ISREC), École Polytechnique Fédérale de Lausanne (EPFL), School of Life Sciences, 1015 Lausanne, Switzerland.
Alexa BurgerInstitute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.
Daniela PanákováElectrochemical Signaling in Development and Disease, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin-Buch, Germany.
Konrad BaslerInstitute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.
Christian MosimannInstitute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.
University of Zurich · CHÉcole Polytechnique Fédérale de Lausanne · CHMax Delbrück Center · DEUniversidad Carlos III de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bcl9 and Pygopus (Pygo) are obligate Wnt/β-catenin cofactors in

Indexed as

Wnt Signaling PathwayAdaptor Proteins, Signal TransducingAnimalsbeta CateninHeartHeart Defects, CongenitalIntracellular Signaling Peptides and ProteinsMiceMutationMyocardiumTranscription FactorsZebrafishZebrafish ProteinsAdaptor Proteins, Signal TransducingBCL9L protein, mouseBCL9 protein, mousebeta CateninIntracellular Signaling Peptides and ProteinsPygo1 protein, mousepygopus 2 protein, mouseTranscription FactorsZebrafish Proteinscardiovascular developmentcongenital heart diseaseCRISPR–Cas9hearttranscriptionWnt signaling

Identifiers

PMID30366904
PMCPMC6217730
OpenAlexW2791843421

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.