Evidence map›Paper›PMID 30366427›Full record

ReviewInternational journal of environmental research and public health2018

Wound Healing Properties of Selected Natural Products.

Nurul 'Izzah Ibrahim, Sok Kuan Wong, Isa Naina Mohamed, Norazlina Mohamed, Kok-Yong Chin, Soelaiman Ima-Nirwana, Ahmad Nazrun Shuid

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed, 1 pooled it
21.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 1 synthesis or guideline pooled it, 323 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. HarnessingFood science & nutrition · 2026
    Review
  4. Callus Induction inPlants (Basel, Switzerland) · 2026
    Article
  5. The effect of Indian costus (Annals of medicine and surgery (2012) · 2026
    Article
  6. Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Evaluation of Biological Effect ofAdvances in pharmacological and pharmaceutical sciences · 2026
    Article
  11. Article
  12. Sea CucumberMarine drugs · 2025
    Article
  13. Review
  14. Article
  15. Polyphenols in wound healing: unlocking prospects with clinical applications.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  16. Article
  17. GC-MS/MS Analysis and Wound Repair Potential ofCurrent pharmaceutical biotechnology · 2025
    Article
  18. Article
  19. Review
  20. Review

56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nurul 'Izzah IbrahimDepartment of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia. nurulizzah88@gmail.com.
Sok Kuan WongDepartment of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia. jocylnwsk@gmail.com.ORCID 0000-0003-1184-4551
Isa Naina MohamedDepartment of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia. isanaina@yahoo.co.uk.
Norazlina MohamedDepartment of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia. azlina@ppukm.ukm.edu.my.ORCID 0000-0003-2480-0224
Kok-Yong ChinDepartment of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia. gabrielchinky@gmail.com.ORCID 0000-0001-6628-1552
Soelaiman Ima-NirwanaDepartment of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia. imasoel@ppukm.ukm.edu.my.
Ahmad Nazrun ShuidDepartment of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia. anazrun@yahoo.com.
University Kebangsaan Malaysia Medical Centre · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound healing is a complex process of recovering the forms and functions of injured tissues. The process is tightly regulated by multiple growth factors and cytokines released at the wound site. Any alterations that disrupt the healing processes would worsen the tissue damage and prolong repair process. Various conditions may contribute to impaired wound healing, including infections, underlying diseases and medications. Numerous studies on the potential of natural products with anti-inflammatory, antioxidant, antibacterial and pro-collagen synthesis properties as wound healing agents have been performed. Their medicinal properties can be contributed by the content of bioactive phytochemical constituents such as alkaloids, essential oils, flavonoids, tannins, saponins, and phenolic compounds in the natural products. This review highlights the in vitro, in vivo and clinical studies on wound healing promotions by the selected natural products and the mechanisms involved.

Indexed as

AnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsBiological ProductsHumansMiceProcollagenRatsWound HealingAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsBiological ProductsProcollagenantibacterialanti-inflammatoryantioxidantcollagenpolyphenolsskin

Identifiers

PMID30366427
PMCPMC6266783
OpenAlexW2898343720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.