Evidence map›Paper›PMID 30366202›Full record

GuidelineCancer treatment reviews2018

Best practices for the management of thymic epithelial tumors: A position paper by the Italian collaborative group for ThYmic MalignanciEs (TYME).

Martina Imbimbo, Margaret Ottaviano, Milena Vitali, Alessandra Fabbri, Giovanni Leuzzi, Michele Fiore, Davide Franceschini, Giulia Pasello, Matteo Perrino, Marco Schiavon and 23 more

Registry-linked trialAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Cancer treatment reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04577495 (Correlation of CT Scan Parameters With Histology, Stage and Prognosis in Surgically-treated Thymomas), which is not on this map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04577495 completednot on this map

Correlation of CT Scan Parameters With Histology, Stage and Prognosis in Surgically-treated Thymomas

TypeobservationalSponsorIRCCS San RaffaeleRan2005 to 2020Enrolled50ConditionsThymoma, Computed Tomography, Staging, Histology
3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Thymic tumors: radiotherapy experience for single institute.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Pediatric Thymoma: A Review and Update of the Literature.Diagnostics (Basel, Switzerland) · 2022
    Review
  15. Article
  16. Article
  17. Thymic tumours and their special features.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

33 authors.

Martina ImbimboUnit of Thoracic Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: martina.imbimbo@istitutotumori.mi.it.
Margaret OttavianoRare Tumors Reference Center, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy.
Milena VitaliUnit of Thoracic Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Alessandra FabbriDepartment of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Giovanni LeuzziThoracic Surgery Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Michele FioreRadiation Oncology, Campus Bio-Medico di Roma, Italy.
Davide FranceschiniRadiotherapy and Radiosurgery Department, Humanitas Clinical and Research Hospital, Rozzano (Milan), Italy.
Giulia PaselloMedical Oncology 2, Istituto Oncologico Veneto IRCCS, Padova, Italy.
Matteo PerrinoDepartment of Medical Oncology, Humanitas Clinical and Research Hospital, Rozzano (Milan), Italy.
Marco SchiavonThoracic Surgery Unit Department of Cardio-Thoracic and Vascular Sciences, University of Padova, Italy.
Giancarlo PruneriDepartment of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Angelo Paolo Dei TosDepartment of Medicine, University of Padua School of Medicine, Italy.
Claudia SangalliDepartment of Radiology and Radiotherapy, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Marina Chiara GarassinoUnit of Thoracic Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Rossana BerardiClinica Oncologica, Università Politecnica delle Marche, Ospedali Riuniti di Ancona, Ancona, Italy.
Alessandra AlessiDepartment of Nuclear Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Giuseppina CalaresoDepartment of Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Iacopo PetriniGeneral Pathology, Department of Translational Research and New Technologies in Medicine, University of Pisa, Italy.
Marta ScorsettiRadiotherapy and Radiosurgery Department, Humanitas Clinical and Research Hospital, Rozzano (Milan), Italy; Humanitas University, Department of Biomedical Sciences, Rozzano (Milan), Italy.
Vieri ScottiDepartment of Oncology, Radiation Oncology Unit, Careggi University Hospital, Florence, Italy.
Lorenzo RossoThoracic Surgery and Lung Transplantation Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, Italy.
Federico ReaThoracic Surgery Unit Department of Cardio-Thoracic and Vascular Sciences, University of Padova, Italy.
Ugo PastorinoThoracic Surgery Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Paolo Giovanni CasaliAdult Mesenchymal Tumor Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Sara RamellaRadiation Oncology, Campus Bio-Medico di Roma, Italy.
Umberto RicardiUniversity of Turin, Italy.
Laura Abate-DagaAssociazione TU.TO.R. Tumori Toracici Rari, Italy.
Valter TorriLaboratory of Methodology for Biomedical Research, IRCCS-Mario Negri Institute for Pharmacological Research, Milan, Italy.
Annalisa TramaEvaluative Epidemiology Unit-Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Giovannella PalmieriRare Tumors Reference Center, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy.
Mirella MarinoDepartment of Pathology, Regina Elena National Cancer Institute, Roma, Italy.
Paolo Andrea ZucaliDepartment of Medical Oncology, Humanitas Clinical and Research Hospital, Rozzano (Milan), Italy.
TYME network collaborators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thymic epithelial tumors (TETs) are a heterogenous group of rare tumors, with a complex histopatological classification. Furthermore, the recent introduction of the first TNM staging system, that is scheduled to replace the Masaoka-Koga system, may create further difficulties in TET management, that remains challenging. Several guidelines for treatment of TETs are available and provide recommendations based mainly on non randomized trials and retrospective or limited series. Often the lack of evidence leads to formulation of indications based on expert opinions. As for other rare cancers it is crucial to create networks to coordinate the work among centres involved in treatment of these diseases in order to offer the best diagnostic and therapeutic tools. For this purpose, in 2014 a network named TYME (ThYmic MalignanciEs), was founded in Italy with the aim of improving care and research in TETs. In September 2017 a panel of multidisciplinary experts from TYME network and from other Italian centres strongly involved in TET diagnosis and treatment convened a first Italian Expert meeting together with representatives of association for patients affected by rare thoracic cancers Tu.To.R, to explore how these tumors are managed in the different centres of Italy compared to ESMO guidelines. In this paper we summarize the issues discussed during that meeting and we propose recommandations based on Masaoka Koga and the new TNM staging system.

Indexed as

Autoimmune DiseasesChemotherapy, AdjuvantContrast MediaFemaleHumansMaleNeoplasm Recurrence, LocalNeoplasms, Glandular and EpithelialThymus NeoplasmsTomography, X-Ray ComputedContrast MediaExpert meetingMasaoka-KogaThymic carcinomaThymic epithelial tumorsThymomaTNM

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.