Evidence map›Paper›PMID 30366152›Full record

ArticleThe journal of pain2019

Pharmacological Modulation of Endogenous Opioid Activity to Attenuate Neuropathic Pain in Rats.

Nai-Jiang Liu, Emiliya M Storman, Alan R Gintzler

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of pain, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Arbiters of endogenous opioid analgesia: role of CNS estrogenic and glutamatergic systems.Translational research : the journal of laboratory and clinical medicine · 2021
    Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nai-Jiang LiuDepartment of Obstetrics and Gynecology, State University of New York, Downstate Medical Center, Brooklyn, New York.
Emiliya M StormanDepartment of Obstetrics and Gynecology, State University of New York, Downstate Medical Center, Brooklyn, New York.
Alan R GintzlerDepartment of Obstetrics and Gynecology, State University of New York, Downstate Medical Center, Brooklyn, New York.. Electronic address: alan.gintzler@downstate.edu.
State University of New York · USSUNY Downstate Health Sciences University · US

Funding

Alternatives to prescription opioids: a precision medicine approach to harnessing endogenous opioids for pain relief and circumvention of prescription opioid abuseR01DA043774 · NIDA · SUNY DOWNSTATE MEDICAL CENTER · PI LIU, NAIJIANG, STEWART, MARK G · 2017 to 2021
$1.8M
NIDA NIH HHS R01 DA043774
6 · The paper itself

Abstract

We showed previously that spinal metabotropic glutamate receptor 1 (mGluR

Indexed as

Chronic PainEstrogen Receptor alphaHyperalgesiaNeuralgiaOligopeptidesReceptors, Metabotropic GlutamateSpinal CordAnimalsAromatase InhibitorsDisease Models, AnimalEstrous CycleFemaleRatsRats, Sprague-DawleyAromatase Inhibitorsendomorphin 2Estrogen Receptor alphametabotropic glutamate receptor type 1OligopeptidesReceptors, Metabotropic GlutamateEndogenous opioidsestrogenic signalingestrous cycleneuropathic painspinal cord

Identifiers

PMID30366152
PMCPMC6447302
OpenAlexW2897461917

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.