ArticleAnalytical biochemistry2019
An accessible and high-throughput strategy of continuously monitoring apoptosis by fluorescent detection of caspase activation.
Article in Analytical biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- 1-Piperidine Propionic Acid Inhibits PAR2/SerpinB3 Signaling and Reduces Glioblastoma Tumor Aggressiveness.International journal of molecular sciences · 2026Article
- Neuroprotection After Intracerebral Hemorrhage: Apoptosis, Neurogenesis, and Prospects of Stem Cell Therapy.Stem cells international · 2026Review
- Lipophilic Cations as Mitochondria-Targeting Moieties: Recent Progress and Design Principles for Medicinal Chemistry.Journal of medicinal chemistry · 2025Review
- Depth-enhanced high-throughput microscopy by compact PSF engineering.Nature communications · 2024Article
- Targeting senescent cells with NKG2D-CAR T cells.Cell death discovery · 2024Article
- Cleaved caspase-3 is present in the majority of glial cells in the intact rat spinal cord during postnatal life.Histochemistry and cell biology · 2024Article
- Multiplexed Live-Cell Imaging for Drug Responses in Patient-Derived Organoid Models of Cancer.Journal of visualized experiments : JoVE · 2024Article
- Multiplexed live-cell imaging for drug responses in patient-derived organoid models of cancer.bioRxiv : the preprint server for biology · 2023Article
- Cholesterol biosynthesis modulates differentiation in murine cranial neural crest cells.Scientific reports · 2023Article
- SynDISCO: A Mechanistic Modeling-Based Framework for Predictive Prioritization of Synergistic Drug Combinations Targeting Cell Signalling Networks.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Ibuprofen and diclofenac differentially affect cell viability, apoptosis and morphology changes of human cholangiocarcinoma cell lines.Journal of Taibah University Medical Sciences · 2022Article
- Quantitative Analysis of Apoptosis and Necrosis in Live Cells Using Flow Cytometry.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Novel Insights into the Roles of Bcl-2 Homolog Nr-13 (vNr-13) Encoded by Herpesvirus of Turkeys in the Virus Replication Cycle, Mitochondrial Networks, and Apoptosis Inhibition.Journal of virology · 2020Article
- Article
- Apoptosis Resistance in Fibroblasts Precedes Progressive Scarring in Pulmonary Fibrosis and Is Partially Mediated by Toll-Like Receptor 4 Activation.Toxicological sciences : an official journal of the Society of Toxicology · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
We present a real-time, high-throughput, and cost-effective method of detecting apoptosis in vitro using a previously developed reagent that detects caspase activation by fluorescence. Current methods of assessing apoptosis fail to account for the dimension of time, and thus are limited in data yielded per sample. This reagent allows real-time detection of apoptosis, but until now has been restricted to a costly automated detection system. Here, we describe apoptosis detection with the Essen Bioscience IncuCyte
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.