Evidence map›Paper›PMID 30365919›Full record

ArticleAnnals of the American Thoracic Society2019

Ambient Air Pollution and Variation in Multiple Domains of Asthma Morbidity among Peruvian Children.

Nadia N Hansel, Karina M Romero, Suzanne L Pollard, Sonali Bose, Kevin J Psoter, Lindsay J Underhill, Caroline Johnson, D'Ann Williams, Frank C Curriero, Patrick Breysse and 3 more

Abstract readMulticenter Study
In one paragraph

Article in Annals of the American Thoracic Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
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  9. Article
  10. Association of PMEnvironmental health : a global access science source · 2020
    Article
  11. Observational
  12. Air Pollution, Asthma, and Sleep Apnea: New Epidemiological Links?Annals of the American Thoracic Society · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Nadia N Hansel1 Division of Pulmonary and Critical Care, and.
Karina M Romero1 Division of Pulmonary and Critical Care, and.
Suzanne L Pollard1 Division of Pulmonary and Critical Care, and.
Sonali Bose1 Division of Pulmonary and Critical Care, and.
Kevin J Psoter4 Division of General Pediatrics and Adolescent Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
Lindsay J Underhill5 Department of Environmental Health and Engineering.
Caroline Johnson6 Department of Global Health, University of Washington, Seattle, Washington.
D'Ann Williams2 Biomedical Research Unit, Asociacion Benefica PRISMA, Lima, Peru.
Frank C Curriero7 Program in Global Disease Epidemiology and Control, Department of International Health, and.
Patrick Breysse2 Biomedical Research Unit, Asociacion Benefica PRISMA, Lima, Peru.
Kirsten Koehler5 Department of Environmental Health and Engineering.
William Checkley1 Division of Pulmonary and Critical Care, and.
GASP Study Investigators
Johns Hopkins University · USPrisma · PEPulmonary and Critical Care Associates · USJohns Hopkins Medicine · USUniversity of Washington · US

Funding

Fogarty Global Health Fellows Coordinating CenterR25TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2012 to 2016
$6.9M
The role of obesity in biological responses to particulate matter in miceP50ES018176 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI HANSEL, NADIA N · 2015 to 2019
$4.8M
Project 3: Dissecting the Diet Asthma Relationship in Mice Models of AsthmaP01ES018176 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI DIETTE, GREGORY B · 2009 to 2013
$4.2M
Genetic Susceptibility to Asthma and IndoorAir Pollution in PeruR01ES018845 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI HANSEL, NADIA N · 2010 to 2014
$3.8M
Acute Lung Injury: Application of Novel Approaches to Longitudinal Data AnalysisR00HL096955 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CHECKLEY, WILLIAM · 2011 to 2013
$723k
FIC NIH HHS R25 TW009340NHLBI NIH HHS R00 HL096955NIEHS NIH HHS P01 ES018176NIEHS NIH HHS P50 ES018176NIEHS NIH HHS R01 ES018845
6 · The paper itself

Abstract

rationaleA large portion of asthma morbidity occurs in low- and middle-income countries, and Peru suffers particularly high asthma prevalence. Ambient air exposures are also high, and likely play a role. Most studies of environmental exposures focus on understanding contributors to health care utilization or mortality risk; however, less severe outcomes may still impact quality of life (QOL).

objectivesTo study the association between multiple pollutants and several asthma domains in Peruvian children.

methodsA total of 484 children aged 9-19 years with asthma were followed for 6-9 months, and evaluated for asthma control, asthma-related QOL, missed school days, and health care utilization. We used geographically distributed monitors to estimate air pollutant concentrations and multivariable generalized linear mixed models to model asthma outcomes as a function of pollutants.

resultsA total of 67% of children had moderate to severe persistent asthma. In multipollutant models, higher particulate matter less than 2.5 μm in aerodynamic diameter (PM

conclusionsOur study highlights the importance of pollutant exposures on multiple domains of asthma morbidity among Peruvian children, including not only acute exacerbations, but also on general asthma burden, such as worse asthma symptom control and QOL.

Indexed as

AdolescentAir PollutionAsthmaChildDisease ProgressionEnvironmental MonitoringFemaleFollow-Up StudiesHumansMaleMorbidityNitrogen DioxideParticulate MatterPeruPrognosisQuality of LifeNitrogen DioxideParticulate Matterair pollutionasthmachildrennitrogen dioxideparticulate matter

Identifiers

PMID30365919
PMCPMC6394121
OpenAlexW2921730575

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.