Evidence map›Paper›PMID 30365646›Full record

ArticleMemorias do Instituto Oswaldo Cruz2018

Dengue 4 in Ceará, Brazil: characterisation of epidemiological and laboratorial aspects and causes of death during the first epidemic in the state.

Izabel Letícia Cavalcante Ramalho, Fernanda Montenegro de Carvalho Araújo, Luciano Pamplona de Góes Cavalcanti, Deborah Nunes Melo Braga, Anne Carolinne Bezerra Perdigão, Flavia Barreto Dos Santos, Fernanda de Bruycker Nogueira, Kiliana Nogueira Farias da Escóssia, Maria Izabel Florindo Guedes

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In one paragraph

Article in Memorias do Instituto Oswaldo Cruz, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Izabel Letícia Cavalcante RamalhoLaboratório Central de Saúde Pública, Setor de Virologia, Fortaleza, CE, Brasil.
Fernanda Montenegro de Carvalho AraújoLaboratório Central de Saúde Pública, Setor de Virologia, Fortaleza, CE, Brasil.
Luciano Pamplona de Góes CavalcantiUniversidade Federal do Ceará, Departamento de Saúde Comunitária, Fortaleza, CE, Brasil.
Deborah Nunes Melo BragaInstituto de Prevenção de Câncer, Fortaleza, CE, Brasil.
Anne Carolinne Bezerra PerdigãoCentro Universitário Christus, Fortaleza, CE, Brasil.
Flavia Barreto Dos SantosInstituto Oswaldo Cruz-Fiocruz, Laboratório de Imunologia Viral, Rio de Janeiro, RJ, Brasil.
Fernanda de Bruycker NogueiraInstituto Oswaldo Cruz-Fiocruz, Laboratório de Imunologia Viral, Rio de Janeiro, RJ, Brasil.
Kiliana Nogueira Farias da EscóssiaSecretaria de Saúde do Estado do Ceará, Núcleo de Vigilância Epidemiológica, Fortaleza, CE, Brasil.
Maria Izabel Florindo GuedesUniversidade Estadual do Ceará, Rede Nordeste de Biotecnologia, Fortaleza, CE, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND The first dengue cases in Brazil with laboratory confirmation occurred in the northern region of the country, with the isolation of two serotypes, dengue virus 1 (DENV-1) and DENV-4. In Ceará, the introduction of DENV-4 was reported during a DENV-1 epidemic in 2011, with only two isolations. OBJECTIVES The aim of this study was to characterise the first DENV-4 epidemic in the state of Ceará, Brazil. METHODS The study population was composed of patients with suspected dengue that were reported to health care units from January to December 2012. The laboratory confirmation of infection was made by viral isolation, reverse transcription polymerase chain reaction (RT-PCR), AgNS1, immunohistochemistry and IgM enzyme-linked immunosorbent assay (ELISA). MAIN CONCLUSIONS In the study year, 72,211 suspected dengue cases were reported and 51,865 of these cases (71.8%) were confirmed to be positive. Co-circulation of three serotypes, DENV-1, DENV-3 and DENV-4, was detected with a predominance of DENV-4 (95.3%). Most cases were not severe, but there were 44 fatal outcomes. DENV-4 Genotype II was identified for the first time in Ceará.

Indexed as

AdolescentAdultAgedAged, 80 and overAge DistributionBrazilCause of DeathChildChild, PreschoolDengueDengue VirusEnzyme-Linked Immunosorbent AssayEpidemicsFemaleHumansImmunohistochemistry

Identifiers

PMID30365646
PMCPMC6193373

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