ArticlePLoS biology2018
Neural timing of stimulus events with microsecond precision.
Article in PLoS biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 36 citations in OpenAlex.
- Reflections on the neural processing of echoes for distance information in echolocating bats.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Review
- Microseconds-level coding of echo delay in the auditory brainstem of an FM-echolocating bat.Journal of neurophysiology · 2024Article
- Bio-inspired designs: leveraging biological brilliance in mechanical engineering-an overview.3 Biotech · 2024Review
- Synthetic data-driven overlapped neural spikes sorting: decomposing hidden spikes from overlapping spikes.Molecular brain · 2024Article
- Multitask learning of a biophysically-detailed neuron model.PLoS computational biology · 2024Article
- Connexin36 RNA Expression in the Cochlear Nucleus of the Echolocating Bat, Eptesicus fuscus.Journal of the Association for Research in Otolaryngology : JARO · 2023Article
- Neural Processing of Naturalistic Echolocation Signals in Bats.Frontiers in neural circuits · 2022Review
- Aging Affects Subcortical Pitch Information Encoding Differently in Humans With Different Language Backgrounds.Frontiers in aging neuroscience · 2022Article
- Doppler shift compensation performance inFrontiers in systems neuroscience · 2022Article
- Effect of background clutter on neural discrimination in the bat auditory midbrain.Journal of neurophysiology · 2021Article
- The fully automated bat (FAB) flight room: A human-free environment for studying navigation in flying bats and its initial application to the retrosplenial cortex.Journal of neuroscience methods · 2021Article
- Temporal coding of echo spectral shape in the bat auditory cortex.PLoS biology · 2020Article
- Objective evidence of temporal processing deficits in older adults.Hearing research · 2020Review
- GABAJournal of neurophysiology · 2020Article
- Evoked potential study of the inferior collicular response to constant frequency-frequency modulation (CF-FM) sounds in FM and CF-FM bats.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2019Article
- Multimodal Modeling of Neural Network Activity: Computing LFP, ECoG, EEG, and MEG Signals With LFPy 2.0.Frontiers in neuroinformatics · 2018Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Temporal analysis of sound is fundamental to auditory processing throughout the animal kingdom. Echolocating bats are powerful models for investigating the underlying mechanisms of auditory temporal processing, as they show microsecond precision in discriminating the timing of acoustic events. However, the neural basis for microsecond auditory discrimination in bats has eluded researchers for decades. Combining extracellular recordings in the midbrain inferior colliculus (IC) and mathematical modeling, we show that microsecond precision in registering stimulus events emerges from synchronous neural firing, revealed through low-latency variability of stimulus-evoked extracellular field potentials (EFPs, 200-600 Hz). The temporal precision of the EFP increases with the number of neurons firing in synchrony. Moreover, there is a functional relationship between the temporal precision of the EFP and the spectrotemporal features of the echolocation calls. In addition, EFP can measure the time difference of simulated echolocation call-echo pairs with microsecond precision. We propose that synchronous firing of populations of neurons operates in diverse species to support temporal analysis for auditory localization and complex sound processing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.